Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.35 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL600747 | 0.99 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL14159199 | 0.88 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL600748 | 0.88 | TSHR (0.53) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL8997482 | 0.82 | ALDH1A1 (0.47) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL828170 | 0.80 | ALDH1A1 (0.48) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL11233083 | 0.80 | TSHR (0.76) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL14028858 | 0.79 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL4265829 | 0.79 | THRB (0.47) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL276446 | 0.79 | TSHR (0.73) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL21605342 | 0.78 | DGKA (0.35) | DGKAP2RY10GPR34PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9034464-B2 | Single layer film and hydrophilic material comprising the same | MITSUI CHEMICALS, INC. (JP) | 2015-05-19 | — | — | US | disclosed |
| US-20130156959-A1 | SINGLE-LAYER FILM AND HYDROPHILIC MATERIAL COMPRISING THE SAME | MITSUI CHEMICALS, INC. (JP) | 2013-06-20 | — | — | US | disclosed |