Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.69 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2019945 | 0.96 | HDAC6 (0.74) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL2015553 | 0.95 | HDAC6 (0.61) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL8400631 | 0.90 | HDAC6 (0.71) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL12973509 | 0.88 | HDAC6 (0.71) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL30714411 | 0.87 | HDAC6 (0.92) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL15744758 | 0.87 | HDAC6 (0.77) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL226988 | 0.87 | HDAC6 (0.92) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL2783279 | 0.86 | HDAC6 (0.90) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL9966133 | 0.86 | HDAC6 (0.79) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL2171472 | 0.86 | HDAC6 (0.79) | HDAC6HDAC1HDAC8HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376394-B2 | Preparation of bendamustine and its salts | DR. REDDY'S LABORATORIES LTD. (IN) | 2016-06-28 | — | — | US | disclosed |
| US-9376394-B2 | Preparation of bendamustine and its salts | DR. REDDY'S LABORATORIES LTD. (IN) | 2016-06-28 | — | — | US | disclosed |
| US-20140142153-A1 | BENDAMUSTINE FORMULATIONS | DR. REDDY'S LABORATORIES, INC. (IN) | 2014-05-22 | — | — | US | disclosed |
| US-20140142153-A1 | BENDAMUSTINE FORMULATIONS | DR. REDDY'S LABORATORIES, INC. (IN) | 2014-05-22 | — | — | US | disclosed |
| US-20140142153-A1 | BENDAMUSTINE FORMULATIONS | DR. REDDY'S LABORATORIES, INC. (IN) | 2014-05-22 | — | — | US | disclosed |
| US-20130158273-A1 | PREPARATION OF BENDAMUSTINE AND ITS SALTS | DR. REDDY'S LABORATORIES, INC. (US) | 2013-06-20 | — | — | US | disclosed |
| US-20130158273-A1 | PREPARATION OF BENDAMUSTINE AND ITS SALTS | DR. REDDY'S LABORATORIES, INC. (US) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158273-A1 | PREPARATION OF BENDAMUSTINE AND ITS SALTS | FOLR1, FOLR2, FLT3 | HDAC6 2271/4885HDAC1 4097/4885HDAC8 3295/4885 |
| US-20140142153-A1 | BENDAMUSTINE FORMULATIONS | MTHFD1, MET, ABCG2 | HDAC6 1831/4885HDAC1 3490/4885HDAC8 2550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.