SCHEMBL15043589

SCHEMBL15043589

Cc1ccc(OF)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 1/20 0.32
HPGD P15428 1/20 0.32
MRGPRX4 Q96LA9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3769995 0.80 TUBB1 (0.44) TUBB1MRGPRX4
SCHEMBL30064 0.78 ACHE (0.42) HPGD
SCHEMBL4549767 0.77 TUBB1 (0.39) TUBB1MRGPRX4
SCHEMBL14289248 0.76 L3MBTL1 (0.41) TUBB1HPGDMRGPRX4
SCHEMBL12386927 0.75 MRGPRX4 (0.35) TUBB1HPGDMRGPRX4
SCHEMBL25821548 0.75 CSNK2A1 (0.34) TUBB1HPGD
SCHEMBL4132417 0.73 HPGD (0.33) HPGDMRGPRX4
SCHEMBL16856007 0.73 GRM8 (0.42) TUBB1
SCHEMBL17146969 0.73 SCN8A (0.32) MRGPRX4
SCHEMBL12172450 0.73 TUBB1 (0.33) TUBB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9617473-B2 Switch element comprising a liquid-crystalline medium MERCK PATENT GMBH (DE) 2017-04-11 US disclosed
US-20130155338-A1 SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-06-20 US disclosed