SCHEMBL150439

SCHEMBL150439

CC(C)(C)c1[c]c(C(C)(C)C)cc(C(C)(C)C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43
POLB P06746 1/20 0.40
HTR1D P28221 2/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.33
GAA P10253 2/20 0.32
MAPT P10636 2/20 0.32
CYP2C19 P33261 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
TYR P14679 1/20 0.32
HTR1B P28222 1/20 0.31
ELANE P08246 1/20 0.31
CD69 Q07108 1/20 0.31
RXRA P19793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3121979 0.87 GABRA1 (0.39) GABRA1GABRB2POLBHTR1DALDH1A1
SCHEMBL248234 0.85 POLB (0.39) GABRA1GABRB2POLBHTR1DTSHR
SCHEMBL1291247 0.81 GABRA1 (0.34) GABRA1GABRB2POLBHTR1DCYP2C19
SCHEMBL11238235 0.81 GABRA1 (0.34) GABRA1GABRB2POLB
SCHEMBL1720320 0.81 HTR1D (0.36) GABRA1GABRB2POLBHTR1DCYP2C19
SCHEMBL887683 0.79 GABRA1 (0.38) GABRA1GABRB2POLBHTR1DRXRA
SCHEMBL27369343 0.79 GABRA1 (0.33) GABRA1GABRB2POLBHTR1D
SCHEMBL4447787 0.79 GABRA1 (0.33) GABRA1GABRB2POLB
SCHEMBL8392140 0.78 GABRA1 (0.32) GABRA1GABRB2POLB
SCHEMBL27341965 0.78 HTR1D (0.38) GABRA1GABRB2POLBHTR1DHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1536 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN claimed
CN-117924370-A Salen ligand coordinated metal Rh catalyst and method for preparing isononyl aldehyde by catalysis of Salen ligand coordinated metal Rh catalyst 中国石油化工股份有限公司 2024-04-26 CN claimed
CN-112424122-B Partially hydrogenated chlorosilanes and process for preparing same by selective hydrogenation 赢创运营有限公司 2024-02-02 CN claimed
US-11827522-B2 Partially hydrogenated chlorosilanes and methods for preparing same by selective hydrogenation EVONIK OPERATIONS GMBH (DE) 2023-11-28 US claimed
CN-117126198-A Bidentate phosphine ligand, and preparation method and application thereof 北京旭阳科技有限公司 2023-11-28 CN claimed
EP-3606528-B1 TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF BROAD INST INC (US) 2023-10-18 EP claimed
EP-3908566-B1 PREPARATION OF 5-ARYL PENTANOLS BASF SE (DE) 2023-07-26 EP claimed
CN-116322986-A Synthesis of pheromone derivatives by Z-selective olefin metathesis 普罗维维公司 2023-06-23 CN claimed
EP-4157814-A1 SYNTHESIS OF PHEROMONE DERIVATIVES VIA Z-SELECTIVE OLEFIN METATHESIS Provivi, Inc. (US) 2023-04-05 EP claimed
CN-114289067-B Binary metal catalyst, preparation method and application thereof 厦门大学 2023-04-04 CN claimed
EP-0570869-B1 Aryl esters of phosphinous acids HOECHST AG (DE) 1997-12-17 EP claimed
US-5596115-A Compounds of rhenium and aluminium, preparation thereof and use thereof as catalysts INSTITUT FRANCAIS DU PETROLE (FR) 1997-01-21 US claimed
EP-0487036-B1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC (US) 1996-02-07 EP claimed
EP-0570869-A2 Aryl esters of phosphinous acids HOECHST AKTIENGESELLSCHAFT (DE) 1993-11-24 EP claimed
EP-0254348-B1 PROCESS OF (CO)POLYMERIZATION OF ALPHA-OLEFINS IN THE PRESENCE OF ANTIOXIDANTS ENICHEM SYNTHESIS S.p.A. (IT) 1993-08-25 EP claimed
US-5162548-A ORGANIC PHOSPHITES SUITABLE AS STABILIZERS FOR POLYMERS HIMONT INCORPORATED (US) 1992-11-10 US claimed
CN-1062540-A Organic phosphites suitable as stabilizers and polymer compositions containing them HIMONT INC (US) 1992-07-08 CN claimed
EP-0487036-A1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC. (US) 1992-05-27 EP claimed
EP-0002821-B1 CYCLIC PHOSPHITES AND ORGANIC MATERIAL STABILIZED BY THEM CIBA-GEIGY AG (CH) 1982-06-23 EP claimed
US-4196117-A Alkylated 1,1'-biphenyl-2,2'-diyl phosphites and stabilized compositions CIBA-GEIGY CORPORATION (US) 1980-04-01 US claimed