SCHEMBL887683

SCHEMBL887683

CC(C)(C)c1[c]c(C(C)(C)C)cc(Cc2cc(C(C)(C)C)cc(C(C)(C)C)c2)c1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
RXRA P19793 2/20 0.34
RXRB P28702 2/20 0.34
RXRG P48443 2/20 0.34
HMGCR P04035 1/20 0.34
HTR1D P28221 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5414773 0.89
SCHEMBL20472890 0.84 GABRA1 (0.50) GABRA1GABRB2RXRARXRBRXRG
SCHEMBL28433211 0.82 GABRA1 (0.48) GABRA1GABRB2RXRARXRBRXRG
SCHEMBL29222655 0.82 GABRA1 (0.48) GABRA1GABRB2RXRARXRBRXRG
SCHEMBL150439 0.79 GABRA1 (0.43) GABRA1GABRB2RXRARXRBRXRG
SCHEMBL11440569 0.78
SCHEMBL284609 0.73 HSPA5 (0.39)
SCHEMBL28264683 0.73 TACR1 (0.46) GABRA1GABRB2RXRARXRBHMGCR
SCHEMBL1291247 0.72 GABRA1 (0.34) GABRA1GABRB2HTR1DPOLB
Phosphoric Acid SCHEMBL30100628 0.72 HMGCR (0.46) GABRA1GABRB2RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10451184-B2 Sliding member and method for producing same NISSAN MOTOR CO., LTD. (JP) 2019-10-22 US disclosed
EP-2949783-B1 SLIDING MEMBER AND METHOD FOR PRODUCING SAME NISSAN MOTOR (JP) 2019-10-09 EP disclosed
EP-1666573-B1 LOW-FRICTION SLIDING MECHANISM AND METHOD OF FRICTION REDUCTION NISSAN MOTOR (JP) 2019-05-15 EP disclosed
CN-104955984-B Sliding member and method for manufacturing same 日产自动车株式会社 2018-06-12 CN disclosed
US-20170335964-A1 SLIDING MEMBER AND METHOD FOR PRODUCING SAME NISSAN MOTOR CO., LTD. (JP) 2017-11-23 US disclosed
US-9759323-B2 Sliding member and method for producing same NISSAN MOTOR CO., LTD. (JP) 2017-09-12 US disclosed
EP-1666572-B1 SYSTEM HAVING DLC CONTACTING FACES, METHOD FOR LUBRICATING THE SYSTEM AND LUBRICATING OIL FOR THE SYSTEM NIPPON OIL CORP (JP) 2017-05-17 EP disclosed
EP-1953214-B1 Lubricant composition comprising a diamond nanoparticle NISSAN MOTOR (JP) 2016-09-14 EP disclosed
US-20150362072-A1 SLIDING MEMBER AND METHOD FOR PRODUCING SAME NISSAN MOTOR CO., LTD. (JP) 2015-12-17 US disclosed
EP-2949783-A1 SLIDING MEMBER AND METHOD FOR PRODUCING SAME NISSAN MOTOR CO., LTD. (JP) 2015-12-02 EP disclosed
EP-1507070-B1 Fuel lubricated sliding mechanism NISSAN MOTOR (JP) 2007-11-21 EP disclosed
US-20070060483-A1 System having dlc contact surfaces, method of lubricating the system, and lubricant for the system (as amended) NIPPON OIL CORPORATION (JP) 2007-03-15 US disclosed
US-20060263604-A1 Low-friction sliding mechanism, low-friction agent composition and method of friction reduction NISSAN MOTOR CO., LTD. (JP) 2006-11-23 US disclosed
EP-1666573-A2 LOW-FRICTION SLIDING MECHANISM, LOW-FRICTION AGENT COMPOSITION AND METHOD OF FRICTION REDUCTION NISSAN MOTOR COMPANY, LIMITED (JP) 2006-06-07 EP disclosed
EP-1666572-A1 SYSTEM HAVING DLC CONTACTING FACES, METHOD FOR LUBRICATING THE SYSTEM AND LUBRICATING OIL FOR THE SYSTEM Nippon Oil Corporation (JP) 2006-06-07 EP disclosed
EP-1661971-A1 SYSTEM HAVING DLC CONTACTING FACES, METHOD FOR LUBRICATING THE SYSTEM AND LUBRICATING OIL FOR THE SYSTEM Nippon Oil Corporation (JP) 2006-05-31 EP disclosed
US-20050089685-A1 Fuel lubricated sliding mechanism NISSAN MOTOR CO., LTD. 2005-04-28 US disclosed
US-20050064196-A1 Low-friction sliding member and low-friction sliding mechanism using same Martin, Jean 2005-03-24 US disclosed
EP-1510594-A2 Low-friction sliding member and low-friction sliding mechanism using same Nissan Motor Co., Ltd. (JP) 2005-03-02 EP disclosed
EP-1507070-A1 Fuel lubricated sliding mechanism Nissan Motor Co., Ltd. (JP) 2005-02-16 EP disclosed