Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1291247 | 0.87 | GABRA1 (0.34) | HTR1DGABRA1GABRB2POLBCYP2C19 | |
| SCHEMBL27369343 | 0.85 | GABRA1 (0.33) | HTR1DGABRA1GABRB2POLB | |
| SCHEMBL27341965 | 0.83 | HTR1D (0.38) | HTR1DGABRA1GABRB2POLB | |
| SCHEMBL150439 | 0.81 | GABRA1 (0.43) | HTR1DGABRA1GABRB2POLBRXRA | |
| SCHEMBL8673176 | 0.79 | — | — | |
| SCHEMBL3121979 | 0.75 | GABRA1 (0.39) | HTR1DGABRA1GABRB2POLB | |
| SCHEMBL248234 | 0.73 | POLB (0.39) | HTR1DGABRA1GABRB2POLB | |
| SCHEMBL4447787 | 0.72 | GABRA1 (0.33) | GABRA1GABRB2POLB | |
| SCHEMBL6567365 | 0.72 | SHBG (0.37) | — | |
| SCHEMBL14672767 | 0.71 | HSPA5 (0.45) | GABRA1GABRB2POLBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1310492-B1 | Phenyl ether-substituted hydroxyphenyl triazine ultraviolet light absorbers | CYTEC TECH CORP (US) | 2012-01-11 | — | — | EP | claimed |
| EP-0358985-A1 | Method of transhalogenating a halophosphorus compound with fluoride | ETHYL CORPORATION (US) | 1990-03-21 | — | — | EP | disclosed |
| EP-0353598-A2 | Transhalogenation of halophosphorus compounds | ETHYL CORPORATION (US) | 1990-02-07 | — | — | EP | disclosed |