Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | IL2 | P60568 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13438531 | 0.89 | TTR (0.44) | ALDH1A1HPGDLMNAKDM4EHSD17B10 | |
| SCHEMBL23071793 | 0.88 | TSHR (0.39) | SMN1; SMN2ALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL23433119 | 0.87 | TSHR (0.39) | SMN1; SMN2LMNAKMT2AMAPTMEN1 | |
| SCHEMBL11990336 | 0.86 | LMNA (0.42) | SMN1; SMN2ALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL21118924 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL4761616 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL23071792 | 0.84 | MEN1 (0.42) | SMN1; SMN2LMNAKMT2AMAPTMEN1 | |
| SCHEMBL19116591 | 0.84 | MEN1 (0.49) | SMN1; SMN2ALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL19116585 | 0.84 | MEN1 (0.49) | SMN1; SMN2ALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL11990499 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1LMNAKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9289510-B2 | Polymeric drug delivery conjugates and methods of making and using thereof | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20130156722-A1 | POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130156722-A1 | POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF | CD44, MMP7, MMP26 | SMN1; SMN2 1711/4885ALDH1A1 779/4885HPGD 994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.