Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22655810 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL21195540 | 0.87 | LMNA (0.38) | LMNASLC6A6CYP2C19BLMALDH1A1 | |
| SCHEMBL778711 | 0.79 | ALOX5AP (0.31) | — | |
| Hydrochloric Acid SCHEMBL21195756 | 0.78 | LMNA (0.31) | LMNASLC6A6CYP2C19BLM | |
| SCHEMBL777574 | 0.77 | CA1 (0.33) | LOXL2LOXCA1CA2 | |
| SCHEMBL2951024 | 0.75 | CA1 (0.32) | LOXL2LOXCA1CA2 | |
| SCHEMBL4444807 | 0.75 | — | — | |
| SCHEMBL8134289 | 0.75 | MMP1 (0.33) | APLNRALDH1A1CA1CA2 | |
| SCHEMBL8142390 | 0.73 | CA12 (0.33) | LOXL2LOXCA1CA2 | |
| SCHEMBL20714713 | 0.71 | MMP1 (0.38) | LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604601-A1 | HETERO RING COMPOUND | Astellas Pharma Inc. (JP) | 2013-06-19 | — | — | EP | disclosed |