SCHEMBL15045367

SCHEMBL15045367

CCC(C)(C)C(=O)Oc1ccc(C(=O)OC(C)C(C)(F)F)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 11/20 0.48
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
ALDH1A1 P00352 2/20 0.37
MAPT P10636 1/20 0.37
TSHR P16473 1/20 0.36
KMT2A Q03164 1/20 0.36
HPGD P15428 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
GAA P10253 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PRTN3 P24158 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10062506 0.92 ELANE (0.48) ELANECA12CA1CA2CA7
SCHEMBL15216265 0.87 ELANE (0.43) ELANECA12CA1CA2CA7
SCHEMBL15216888 0.79 ELANE (0.43) ELANECA12CA1CA2CA7
SCHEMBL1104226 0.79 ELANE (0.56) ELANECA12CA1CA2CA7
SCHEMBL14649722 0.78 ELANE (0.54) ELANECA12CA1CA2CA7
SCHEMBL21208347 0.78 ELANE (0.47) ELANEALDH1A1MAPTGAAL3MBTL1
SCHEMBL17853773 0.78 ELANE (0.47) ELANEALDH1A1MAPTGAAL3MBTL1
SCHEMBL1104189 0.77 CA12 (0.57) ELANECA12CA1CA2CA7
SCHEMBL10064124 0.77 ELANE (0.55) ELANECA12CA1CA2CA9
SCHEMBL15216272 0.77 ELANE (0.37) ELANECA2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8778595-B2 Resist composition, method of forming resist pattern, and polymeric compound TOKYO OHKA KOGYO CO., LTD. (JP) 2014-07-15 US disclosed
US-20130157201-A1 RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, AND POLYMERIC COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2013-06-20 US disclosed