SCHEMBL15046367

SCHEMBL15046367

Brc1ccc(-c2ccc(N(c3ccccc3)c3ccccc3)cn2)nc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.39
KDM4E B2RXH2 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
MAPT P10636 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
CYP11B1 P15538 1/20 0.38
GBA1 P04062 2/20 0.37
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
CRHBP P24387 1/20 0.34
ATM Q13315 1/20 0.34
CRHR2 Q13324 1/20 0.34
TLR9 Q9NR96 1/20 0.34
SMN1; SMN2 Q16637 5/20 0.34
NPC1 O15118 5/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL787234 0.88 CYP11B1 (0.49) ALDH1A1KDM4EL3MBTL1MAPTTDP1
SCHEMBL18859342 0.86 CYP11B1 (0.45) ALDH1A1KDM4EL3MBTL1MAPTTDP1
SCHEMBL15498051 0.86 CYP11B1 (0.48) ALDH1A1KDM4EL3MBTL1MAPTTDP1
SCHEMBL19784800 0.83 NPC1 (0.47) ALDH1A1KDM4EL3MBTL1MAPTTDP1
SCHEMBL17402668 0.81 NPC1 (0.49) ALDH1A1L3MBTL1CYP11B1SMN1; SMN2NPC1
SCHEMBL19185482 0.80 KDM4E (0.52) ALDH1A1KDM4EL3MBTL1MAPTTDP1
SCHEMBL15421297 0.79 CYP11B1 (0.50) ALDH1A1KDM4EL3MBTL1MAPTTDP1
SCHEMBL15643374 0.77 ALDH1A1 (0.45) ALDH1A1KDM4EL3MBTL1MAPTTDP1
SCHEMBL15687666 0.76 ALDH1A1 (0.56) ALDH1A1KDM4EL3MBTL1MAPTTDP1
SCHEMBL15907013 0.76 ALDH1A1 (0.56) ALDH1A1KDM4EL3MBTL1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013089460-A1 NOVEL CHEMICAL COMPOUND HAVING AN ACRIDINE STRUCTURE, AND ORGANIC LIGHT-EMITTING DIODE USING SAME 주식회사 두산 (KR) 2013-06-20 WO disclosed