SCHEMBL787234

SCHEMBL787234

Brc1ccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)nc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 4/20 0.49
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
NFKB1 P19838 2/20 0.43
NFKB2 Q00653 2/20 0.43
RELA Q04206 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MAPK1 P28482 2/20 0.43
LDHA P00338 1/20 0.39
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HPGDS O60760 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15498051 0.98 CYP11B1 (0.48) CYP11B1NPC1RAB9ANFKB1NFKB2
SCHEMBL19784800 0.89 NPC1 (0.47) CYP11B1NPC1RAB9ANFKB1NFKB2
SCHEMBL18859342 0.88 CYP11B1 (0.45) CYP11B1NPC1RAB9ANFKB1NFKB2
SCHEMBL15046367 0.88 ALDH1A1 (0.39) CYP11B1NPC1RAB9ANFKB1NFKB2
SCHEMBL17402668 0.87 NPC1 (0.49) CYP11B1NPC1RAB9ANFKB1NFKB2
SCHEMBL610726 0.85 CYP11B1 (0.54) CYP11B1NPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL15498078 0.85 MAPK1 (0.45) CYP11B1NPC1RAB9ANFKB1NFKB2
SCHEMBL12523554 0.83 MAPK1 (0.56) CYP11B1NPC1RAB9ANFKB1NFKB2
SCHEMBL15498029 0.83 MAPK1 (0.44) CYP11B1NPC1RAB9ANFKB1NFKB2
SCHEMBL15498079 0.83 CYP11B1 (0.38) CYP11B1NPC1RAB9ANFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11800790-B2 Monocarborane cluster-containing platinum complexes and preparation method and OLED application GUANGXI MINZU UNIVERSITY (CN) 2023-10-24 US disclosed
US-11800790-B2 Monocarborane cluster-containing platinum complexes and preparation method and OLED application GUANGXI MINZU UNIVERSITY (CN) 2023-10-24 US disclosed
EP-2681970-B1 POROUS FILMS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORP (JP) 2018-01-17 EP disclosed
EP-2681970-B1 POROUS FILMS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORP (JP) 2018-01-17 EP disclosed
EP-2616457-B1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORP (JP) 2016-06-22 EP disclosed
EP-2616457-B1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORP (JP) 2016-06-22 EP disclosed
US-9328086-B2 Substituted bipyridines for use in organic light-emitting devices NITTO DENKO CORPORATION (JP) 2016-05-03 US disclosed
US-9328086-B2 Substituted bipyridines for use in organic light-emitting devices NITTO DENKO CORPORATION (JP) 2016-05-03 US disclosed
US-9328086-B2 Substituted bipyridines for use in organic light-emitting devices NITTO DENKO CORPORATION (JP) 2016-05-03 US disclosed
US-9172051-B2 Organic light emitting host materials NITTO DENKO CORPORATION (JP) 2015-10-27 US disclosed
US-20140066627-A1 ORGANIC LIGHT EMITTING HOST MATERIALS NITTO DENKO CORPORATION (JP) 2014-03-06 US disclosed
EP-2616457-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES Nitto Denko Corporation (JP) 2013-07-24 EP disclosed
WO-2012119111-A1 POROUS FILMS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-09-07 WO disclosed
WO-2012119111-A1 POROUS FILMS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-09-07 WO disclosed
US-20120223635-A1 POROUS FILMS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-09-06 US disclosed
US-20120179089-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-07-12 US disclosed
US-20120179089-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-07-12 US disclosed
US-20120179089-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-07-12 US disclosed
WO-2012037269-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-03-22 WO disclosed
WO-2012037269-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11800790-B2 Monocarborane cluster-containing platinum complexes and preparation method and OLED application OXA1L, OCIAD1, OCIAD2 CYP11B1 85/4885NPC1 1503/4885RAB9A 3697/4885
US-20120179089-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES BRD9, PIR, BRD2 CYP11B1 4030/4885NPC1 4104/4885RAB9A 3592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.