SCHEMBL19784800

SCHEMBL19784800

Brc1ccc(-c2ccc(N(c3ccccc3)c3ccc(-c4ccccc4)nc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
NFKB1 P19838 2/20 0.47
NFKB2 Q00653 2/20 0.47
RELA Q04206 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MAPK1 P28482 2/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP11B1 P15538 4/20 0.46
L3MBTL1 Q9Y468 2/20 0.43
MCL1 Q07820 1/20 0.39
LDHA P00338 1/20 0.39
HPGDS O60760 1/20 0.39
NLRP3 Q96P20 1/20 0.39
AGTR1 P30556 1/20 0.39
CYP11B2 P19099 3/20 0.36
TP53 P04637 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17402668 0.98 NPC1 (0.49) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL18859342 0.97 CYP11B1 (0.45) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL15498051 0.90 CYP11B1 (0.48) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL787234 0.89 CYP11B1 (0.49) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL15421297 0.88 CYP11B1 (0.50) RAB9AALDH1A1CYP11B1L3MBTL1LDHA
SCHEMBL17402612 0.84 CYP2A6 (0.39) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL17465478 0.84 CYP11B1 (0.45) ALDH1A1CYP11B1L3MBTL1LDHAHPGDS
SCHEMBL15046367 0.83 ALDH1A1 (0.39) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL15907007 0.83 ALDH1A1 (0.68) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL17165567 0.83 ALDH1A1 (0.68) NPC1RAB9ANFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018012780-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2018-01-18 WO disclosed