Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 18/20 | 0.71 |
| ▸ | EGFR | P00533 | 17/20 | 0.71 |
| ▸ | BRAF | P15056 | 3/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1504794 | 0.93 | EGFR (0.71) | KDREGFRBRAF | |
| SCHEMBL1504863 | 0.91 | KDR (0.58) | KDREGFRBRAF | |
| SCHEMBL3947459 | 0.89 | KDR (0.61) | KDREGFRBRAF | |
| SCHEMBL1504807 | 0.89 | EGFR (0.61) | KDREGFRBRAF | |
| SCHEMBL1504947 | 0.89 | KDR (0.62) | KDREGFRBRAF | |
| SCHEMBL1504960 | 0.89 | EGFR (0.69) | KDREGFRBRAF | |
| SCHEMBL3953826 | 0.89 | AURKA (0.63) | KDREGFRBRAF | |
| SCHEMBL3948584 | 0.88 | KDR (0.58) | KDREGFRBRAF | |
| SCHEMBL1505014 | 0.88 | EGFR (0.60) | KDREGFR | |
| SCHEMBL3954388 | 0.87 | EGFR (0.59) | KDREGFRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011033094-A1 | SCHEDULE OF ADMINISTRATION OF BENZAZOLE DERIVATIVES IN THE TREATMENT OF LEUKEMIAS | 4SC AG (DE) | 2011-03-24 | — | — | WO | claimed |