Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 13/20 | 0.61 |
| ▸ | EGFR | P00533 | 11/20 | 0.61 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | BRAF | P15056 | 4/20 | 0.59 |
| ▸ | AURKA | O14965 | 7/20 | 0.58 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.58 |
| ▸ | FLT4 | P35916 | 2/20 | 0.58 |
| ▸ | TEK | Q02763 | 2/20 | 0.58 |
| ▸ | RAF1 | P04049 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947281 | 0.95 | EGFR (0.69) | KDREGFRSRCBRAFAURKA | |
| SCHEMBL3949805 | 0.94 | KDR (0.70) | KDREGFRSRCBRAFAURKA | |
| SCHEMBL3953826 | 0.93 | AURKA (0.63) | KDREGFRSRCBRAFAURKA | |
| SCHEMBL3946268 | 0.92 | AURKA (0.64) | KDREGFRBRAFAURKAAURKB | |
| SCHEMBL1504960 | 0.91 | EGFR (0.69) | KDREGFRSRCBRAFAURKA | |
| SCHEMBL3954388 | 0.91 | EGFR (0.59) | KDREGFRBRAFAURKAAURKB | |
| SCHEMBL1504836 | 0.89 | KDR (0.71) | KDREGFRBRAF | |
| SCHEMBL3946804 | 0.89 | EGFR (0.78) | KDREGFRAURKAAURKBERBB2 | |
| SCHEMBL1504794 | 0.89 | EGFR (0.71) | KDREGFRSRCBRAFAURKA | |
| SCHEMBL3946532 | 0.89 | KDR (0.74) | KDREGFRSRCBRAFFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514460-B2 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2009-04-07 | — | — | US | disclosed |
| US-7514460-B2 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2009-04-07 | — | — | US | disclosed |
| US-7514460-B2 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2009-04-07 | — | — | US | disclosed |
| US-20060135782-A1 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135782-A1 | Benzazole analogues and uses thereof | DCK, SBK3, DAPK3 | KDR 1657/4885EGFR 437/4885SRC 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.