SCHEMBL15048706

SCHEMBL15048706

CC(N)C(=O)OC(COC(=O)CCCc1ccccc1)COC(=O)CCCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.53
ADRB1 P08588 1/20 0.53
ADRB3 P13945 1/20 0.53
TLR2 O60603 2/20 0.48
FAAH O00519 5/20 0.47
LPAR1 Q92633 3/20 0.47
ALOX5 P09917 1/20 0.47
TDP1 Q9NUW8 3/20 0.45
KMT2A Q03164 1/20 0.45
HDAC3 O15379 1/20 0.44
MAPK1 P28482 1/20 0.44
ADRA1A P35348 1/20 0.44
HDAC4 P56524 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HDAC1 Q13547 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15061850 1.00 ADRB2 (0.53) ADRB2ADRB1ADRB3TLR2FAAH
SCHEMBL15061845 1.00 ADRB2 (0.53) ADRB2ADRB1ADRB3TLR2FAAH
SCHEMBL15061853 0.90 TLR2 (0.48) ADRB2ADRB1ADRB3TLR2FAAH
SCHEMBL15048720 0.90 TLR2 (0.48) ADRB2ADRB1ADRB3TLR2FAAH
Glycerol Phenylbutyrate SCHEMBL10102804 0.86 ADRB2 (0.56) ADRB2ADRB1ADRB3TLR2FAAH
SCHEMBL15061849 0.84 ADRB2 (0.62) ADRB2ADRB1ADRB3FAAHLPAR1
SCHEMBL15048824 0.84 ADRB2 (0.62) ADRB2ADRB1ADRB3FAAHLPAR1
SCHEMBL15049350 0.83 LPAR1 (0.53) ADRB2ADRB1ADRB3TLR2FAAH
SCHEMBL15061856 0.83 LPAR1 (0.53) ADRB2ADRB1ADRB3TLR2FAAH
SCHEMBL3784212 0.83 ALDH1A1 (0.56) ADRB2ADRB1ADRB3TLR2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2607366-A1 Glycerol phenyl butyrate esters Lunamed AG (CH) 2013-06-26 EP disclosed