Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 6/20 | 0.61 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.46 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CTH | P32929 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15062082 | 0.85 | CAPN1 (0.47) | CAPN1CTHCTSSRAB9ASMN1; SMN2 | |
| SCHEMBL11178096 | 0.78 | SUCNR1 (0.52) | CAPN1SUCNR1CAPN9CTSBMAPK1 | |
| SCHEMBL6069649 | 0.78 | SUCNR1 (0.52) | CAPN1SUCNR1CAPN9CTSBMAPK1 | |
| SCHEMBL15062075 | 0.78 | CAPN1 (0.46) | CAPN1CTSBCTHCTSLTSHR | |
| SCHEMBL15171443 | 0.77 | CAPN1 (1.00) | CAPN1CAPN9CTSBMAPK1CTSK | |
| SCHEMBL11171510 | 0.76 | SUCNR1 (0.50) | CAPN1SUCNR1CAPN9CTSBMAPK1 | |
| SCHEMBL4902697 | 0.74 | SUCNR1 (0.48) | CAPN1SUCNR1CAPN9CTSBMAPK1 | |
| SCHEMBL1121704 | 0.74 | SUCNR1 (0.48) | CAPN1SUCNR1CAPN9CTSBMAPK1 | |
| SCHEMBL17846598 | 0.72 | FNTA (0.39) | CAPN1LMNAMAPTMAOBKDM4E | |
| SCHEMBL23961741 | 0.72 | SUCNR1 (0.44) | CAPN1SUCNR1CAPN9CTSBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607361-A1 | Thiirane and michael acceptor compounds and their medical use | Ludwig-Maximilians-Universität München (DE) | 2013-06-26 | — | — | EP | disclosed |