Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.44 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1121704 | 1.00 | SUCNR1 (0.48) | SUCNR1CAPN1CAPN9CTSBMAPK1 | |
| SCHEMBL11165832 | 0.87 | POLB (0.44) | SUCNR1CAPN1CAPN9CTSBMAPK1 | |
| SCHEMBL11176189 | 0.85 | POLB (0.50) | POLBEPHX1 | |
| SCHEMBL11178096 | 0.83 | SUCNR1 (0.52) | SUCNR1CAPN1CAPN9CTSBMAPK1 | |
| SCHEMBL6069649 | 0.83 | SUCNR1 (0.52) | SUCNR1CAPN1CAPN9CTSBMAPK1 | |
| SCHEMBL11171510 | 0.82 | SUCNR1 (0.50) | SUCNR1CAPN1CAPN9CTSBMAPK1 | |
| SCHEMBL11178934 | 0.79 | CAPN1 (0.67) | SUCNR1CAPN1CAPN9CTSBMAPK1 | |
| SCHEMBL16488181 | 0.79 | CHRNB2 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL14067709 | 0.78 | CAPN1 (0.51) | CAPN1CTSBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11174784 | 0.78 | CAPN1 (0.65) | SUCNR1CAPN1CAPN9CTSBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210228699-A1 | COMPOSITIONS AND METHODS FOR TARGETED IMMUNOTHERAPY | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-07-29 | — | — | US | disclosed |
| US-20080227806-A1 | Novel Drugs for Dementia | AMERICAN LIFE SCIENCE PHARMACEUTICALS (US) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227806-A1 | Novel Drugs for Dementia | CTSS, PRSS1, CBS | SUCNR1 2175/4885CAPN1 273/4885CAPN9 428/4885 |
| US-20210228699-A1 | COMPOSITIONS AND METHODS FOR TARGETED IMMUNOTHERAPY | TP53, CD47, MSH2 | SUCNR1 4548/4885CAPN1 1325/4885CAPN9 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.