Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 10/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PPM1B | O75688 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.34 |
| ▸ | CTH | P32929 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14067709 | 0.80 | CAPN1 (0.51) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL11171419 | 0.80 | CAPN1 (0.51) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL2387697 | 0.78 | TSHR (0.55) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL5317413 | 0.78 | TSHR (0.55) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL2387688 | 0.78 | TSHR (0.55) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL2387693 | 0.78 | TSHR (0.55) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL11545787 | 0.78 | TSHR (0.55) | CAPN1CTSLCTSBLMNACTSG | |
| SCHEMBL15062082 | 0.78 | CAPN1 (0.47) | CAPN1CTH | |
| SCHEMBL15048739 | 0.78 | CAPN1 (0.61) | CAPN1CTSLCTSBLMNATSHR | |
| SCHEMBL7047730 | 0.78 | CAPN1 (0.48) | CAPN1CTSLCTSBLMNACTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607361-A1 | Thiirane and michael acceptor compounds and their medical use | Ludwig-Maximilians-Universität München (DE) | 2013-06-26 | — | — | EP | disclosed |