Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | CTH | P32929 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15048739 | 0.85 | CAPN1 (0.61) | CAPN1CTHRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15062075 | 0.78 | CAPN1 (0.46) | CAPN1CTH | |
| SCHEMBL17846598 | 0.72 | FNTA (0.39) | CAPN1MAOBMAOACA12CA1 | |
| SCHEMBL12370963 | 0.71 | — | — | |
| SCHEMBL15171365 | 0.69 | CAPN1 (0.38) | CAPN1CTH | |
| SCHEMBL5554522 | 0.69 | — | — | |
| SCHEMBL474814 | 0.67 | — | — | |
| SCHEMBL9816683 | 0.66 | KDM1A (0.36) | CTHRAB9ASMN1; SMN2NPC1MAOB | |
| SCHEMBL3964083 | 0.65 | SMN1; SMN2 (0.57) | CTHSMN1; SMN2 | |
| SCHEMBL31120967 | 0.65 | CTH (0.49) | CAPN1CTHRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607361-A1 | Thiirane and michael acceptor compounds and their medical use | Ludwig-Maximilians-Universität München (DE) | 2013-06-26 | — | — | EP | disclosed |