Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959110 | 0.86 | MAPT (0.54) | HTTLMNAKMT2AMEN1NR1I2 | |
| SCHEMBL1505106 | 0.86 | ALDH1A1 (0.49) | HTTLMNAKMT2AKDM4EHPGD | |
| SCHEMBL25399393 | 0.83 | LMNA (0.47) | HTTLMNAKMT2AMEN1NR1I2 | |
| SCHEMBL31565683 | 0.83 | MAPK1 (0.50) | HTTLMNAKMT2AMEN1NR1I2 | |
| SCHEMBL12505380 | 0.82 | LMNA (0.48) | LMNAKMT2AMEN1MAPTHTR2B | |
| SCHEMBL23835432 | 0.81 | LMNA (0.67) | HTTLMNAKMT2AMEN1NR1I2 | |
| SCHEMBL1327202 | 0.80 | PIN1 (0.50) | HTTLMNAKMT2AMEN1CYP3A4 | |
| SCHEMBL29406733 | 0.80 | PIN1 (0.50) | HTTLMNAKMT2AMEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL31328997 | 0.79 | PIN1 (0.49) | HTTLMNAKMT2AMEN1CYP3A4 | |
| SCHEMBL8334827 | 0.78 | PTGDR2 (0.46) | HTTLMNAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011027156-A1 | BENZODIAZEPINE DERIVATIVES FOR TREATING HEPATITIS C INFECTION | ARROW THERAPEUTICS LIMITED (GB) | 2011-03-10 | — | — | WO | disclosed |