Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2413026 | 0.93 | PTGS2 (0.50) | TNKS2PTGS2PTGS1SHBGCA1 | |
| SCHEMBL2410617 | 0.91 | PTGS2 (0.48) | TNKS2PTGS2PTGS1SHBGCA1 | |
| SCHEMBL12761147 | 0.91 | PTGS2 (0.48) | TNKS2PTGS2PTGS1SHBGCA1 | |
| SCHEMBL10366946 | 0.90 | ALDH1A1 (0.52) | TNKS2PTGS2PTGS1SHBGCA1 | |
| SCHEMBL2570939 | 0.88 | PTGS2 (0.57) | TNKS2PTGS2PTGS1SHBGCA1 | |
| SCHEMBL8846095 | 0.88 | PTGS2 (0.57) | TNKS2PTGS2PTGS1SHBGCA1 | |
| SCHEMBL13899759 | 0.86 | SHBG (0.56) | TNKS2PTGS2PTGS1SHBGNPC1 | |
| SCHEMBL8462396 | 0.86 | PTGS1 (0.55) | TNKS2PTGS2PTGS1SHBGCA1 | |
| SCHEMBL28232927 | 0.86 | PTGS2 (0.55) | PTGS2PTGS1SHBGCA1CA2 | |
| SCHEMBL13899768 | 0.85 | TNKS2 (0.45) | TNKS2PTGS2PTGS1SHBGCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2110370-B1 | Method of producing p-hydroxyphenylalkanols | SUMITOMO CHEMICAL CO (JP) | 2010-09-01 | — | — | EP | disclosed |
| EP-1348686-B1 | Method of producing p-hydroxyphenylalkanols | SUMITOMO CHEMICAL CO (JP) | 2010-03-03 | — | — | EP | disclosed |
| EP-2110370-A1 | Method of producing p-hydroxyphenylalkanols | Sumitomo Chemical Company, Limited (JP) | 2009-10-21 | — | — | EP | disclosed |
| CN-1307139-C | Method of producing p-hydroxyphenylalkanols | SUMITOMO CHEMICAL CO (JP) | 2007-03-28 | — | — | CN | disclosed |
| US-6717020-B2 | HIGH YIELD REACTION OF PHENOLS AND UNSATURATED ALCOHOLS IN PRESENCE OF SUCH AS TITANIUM TETRAETHOXIDE AND SODIUM METHOXIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-04-06 | — | — | US | disclosed |
| US-20030195379-A1 | Method of producing p-Hydroxyphenylalkanols | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-10-16 | — | — | US | disclosed |
| CN-1448379-A | Method of producing p-hydroxyphenylalkanols | SUMITOMO CHEMICAL CO (JP) | 2003-10-15 | — | — | CN | disclosed |
| EP-1348686-A1 | Method of producing p-hydroxyphenylalkanols | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-10-01 | — | — | EP | disclosed |
| US-5876851-A | PROTECTIVE COATING ON METAL | TEIJIN LIMITED (JP) | 1999-03-02 | — | — | US | disclosed |
| EP-0653455-B1 | FILM FOR METAL LAMINATION | TEIJIN LTD (JP) | 1997-10-01 | — | — | EP | disclosed |
| EP-0653455-A1 | FILM FOR METAL LAMINATION | TEIJIN LIMITED (JP) | 1995-05-17 | — | — | EP | disclosed |
| EP-0636647-A1 | Use of substituted phenols as fatique protectors for dynamically stressed elastomers | BAYER AG (DE) | 1995-02-01 | — | — | EP | disclosed |
| US-5120843-A | Nervous system disorders | UPJOHN (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0487510-A1 | Pharmaceutically active amines | THE UPJOHN COMPANY (US) | 1992-05-27 | — | — | EP | disclosed |
| EP-0358676-A1 | PHARMACEUTICALLY ACTIVE AMINES | THE UPJOHN COMPANY (US) | 1990-03-21 | — | — | EP | disclosed |
| EP-0293078-A1 | Pharmaceutically active amines | THE UPJOHN COMPANY (US) | 1988-11-30 | — | — | EP | disclosed |
| WO-1988008424-A1 | PHARMACEUTICALLY ACTIVE AMINES | THE UPJOHN COMPANY (US) | 1988-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195379-A1 | Method of producing p-Hydroxyphenylalkanols | ADH1C, NR1H3, ADH5 | TNKS2 3493/4885PTGS2 345/4885PTGS1 397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.