SCHEMBL15052302

SCHEMBL15052302

O=C(Nc1ccccc1NC1C2CC3CC(C2)CC1C3)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.56
KDM1A O60341 1/20 0.49
EPHX2 P34913 1/20 0.48
MDM4 O15151 1/20 0.47
TP53 P04637 1/20 0.47
HDAC3 O15379 1/20 0.47
MAPK1 P28482 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
POLB P06746 1/20 0.47
HPGD P15428 1/20 0.47
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
MEN1 O00255 3/20 0.45
FAAH O00519 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1675682 0.78 KMT2A (0.74) KMT2AEPHX2MEN1FAAH
SCHEMBL1072522 0.77 BRD4 (0.49) KMT2AEPHX2HPGDRAB9ACYP1A2
SCHEMBL1110180 0.77 MDM4 (0.73) KMT2AMDM4TP53HDAC3MAPK1
SCHEMBL8618469 0.73 EPHX2 (0.47) KMT2AEPHX2TP53MAPK1HPGD
SCHEMBL2086933 0.72 BRD4 (0.52) KMT2AEPHX2CYP3A4CYP2C9CYP2C19
SCHEMBL10953014 0.71 HDAC3 (0.71) KMT2AKDM1AMDM4TP53HDAC3
SCHEMBL19375492 0.71 KMT2A (0.40) KMT2AEPHX2CYP3A4CYP2C9CYP2C19
SCHEMBL15052202 0.69 KDM4E (0.49) KMT2AEPHX2TP53HPGDCYP1A2
SCHEMBL3794850 0.69 NPC1 (0.74) KMT2AMDM4TP53HDAC3MAPK1
SCHEMBL29960964 0.69 NPC1 (0.74) KMT2AMDM4TP53HDAC3MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9768396-B2 Iridium complex, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-09-19 US disclosed
US-9768396-B2 Iridium complex, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-09-19 US disclosed
US-20130161598-A1 Iridium Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-06-27 US disclosed
US-20130161598-A1 Iridium Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-06-27 US disclosed