SCHEMBL1675682

SCHEMBL1675682

O=C(NC1C2CC3CC(C2)CC1C3)c1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.74
EPHX2 P34913 6/20 0.56
HSD11B1 P28845 3/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
FAAH O00519 2/20 0.56
CNR1 P21554 1/20 0.53
CNR2 P34972 1/20 0.53
MEN1 O00255 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL241938 0.84 L3MBTL1 (0.58) KMT2AEPHX2HSD11B1L3MBTL1FAAH
SCHEMBL238713 0.83 L3MBTL1 (0.57) KMT2AEPHX2HSD11B1L3MBTL1CNR1
SCHEMBL1675968 0.83 KMT2A (0.57) KMT2AEPHX2HSD11B1L3MBTL1FAAH
SCHEMBL19808151 0.83 HSD11B1 (0.54) KMT2AEPHX2HSD11B1L3MBTL1FAAH
SCHEMBL1761711 0.82 KMT2A (0.54) KMT2AEPHX2FAAHCNR1CNR2
SCHEMBL14082229 0.82 KMT2A (0.53) KMT2AHSD11B1L3MBTL1FAAH
SCHEMBL16530082 0.81 HSD11B1 (0.57) KMT2AEPHX2HSD11B1FAAH
SCHEMBL1675970 0.81 HSD11B1 (0.57) KMT2AEPHX2HSD11B1FAAH
SCHEMBL4608538 0.79 KMT2A (0.54) KMT2AEPHX2HSD11B1L3MBTL1CNR1
SCHEMBL4396722 0.79 KMT2A (0.53) KMT2AEPHX2HSD11B1L3MBTL1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3239131-A1 NEW COMPOUNDS WITH ACTIVITY THAT PROTECTS AGAINST THE ACTION OF TOXINS AND VIRUSES IN INTRACELLULAR ACTION MODE Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2017-11-01 EP claimed
US-20170233386-A1 Compounds Which Have a Protective Activity with Respect to the Action of Toxins and of Viruses with an Intracellular Mode of Action COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2017-08-17 US claimed
US-20160083355-A1 COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION COMMISSARIAT ENERGIE ATOMIQUE (FR) 2016-03-24 US claimed
US-8383381-B2 Method for producing hydroxylated adaivjantane using cytochrome P450 Shjonogi & Co., Ltd. (JP) 2013-02-26 US claimed
US-20120283249-A1 Novel compounds which have a protective activity with respect to the action of toxins and of viruses with an intracellular mode of action COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2012-11-08 US claimed
US-20110086405-A1 METHOD FOR PRODUCING HYDROXYLATED ADAMANTANE USING CYTOCHROME P450 SHIONOGI & CO., LTD. (JP) 2011-04-14 US claimed
CN-101878306-A Method for producing hydroxylated adamantane using cytochrome P450 SHIONOGI & CO 2010-11-03 CN claimed
EP-2221380-A1 METHOD FOR PRODUCING HYDROXYLATED ADAMANTANE USING CYTOCHROME P450 Shionogi & Co., Ltd. (JP) 2010-08-25 EP claimed
EP-2145873-A1 New compounds with activity that protects against the action of toxins and viruses in intracellular action mode COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2010-01-20 EP claimed
CN-117050689-B Preparation method and application of conductive polymer adhesive 江苏理工学院 2024-03-19 CN disclosed
CN-117050689-A Preparation method and application of conductive polymer adhesive 江苏理工学院 2023-11-14 CN disclosed
US-10202388-B2 Fused-ring compounds, pharmaceutical composition and uses thereof Shanghai De Novo Pharmatech Co., Ltd. (CN) 2019-02-12 US disclosed
US-20180022752-A1 FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF Shanghai De Novo Pharmatech Co., Ltd. (CN) 2018-01-25 US disclosed
EP-3239131-A1 NEW COMPOUNDS WITH ACTIVITY THAT PROTECTS AGAINST THE ACTION OF TOXINS AND VIRUSES IN INTRACELLULAR ACTION MODE Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2017-11-01 EP disclosed
CN-101878306-A Method for producing hydroxylated adamantane using cytochrome P450 SHIONOGI & CO 2010-11-03 CN disclosed
EP-2221380-A1 METHOD FOR PRODUCING HYDROXYLATED ADAMANTANE USING CYTOCHROME P450 Shionogi & Co., Ltd. (JP) 2010-08-25 EP disclosed
EP-2221380-A1 METHOD FOR PRODUCING HYDROXYLATED ADAMANTANE USING CYTOCHROME P450 Shionogi & Co., Ltd. (JP) 2010-08-25 EP disclosed
EP-2145873-A1 New compounds with activity that protects against the action of toxins and viruses in intracellular action mode COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2010-01-20 EP disclosed
EP-2145873-A1 New compounds with activity that protects against the action of toxins and viruses in intracellular action mode COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2010-01-20 EP disclosed
WO-2009041470-A1 METHOD FOR PRODUCING HYDROXYLATED ADAMANTANE USING CYTOCHROME P450 SHIONOGI & CO., LTD. (JP) 2009-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120283249-A1 Novel compounds which have a protective activity with respect to the action of toxins and of viruses with an intracellular mode of action HAVCR2, MAVS, ANTXR2 KMT2A 4248/4885EPHX2 4659/4885HSD11B1 4709/4885
US-20160083355-A1 COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION HAVCR2, MAVS, ANTXR2 KMT2A 4212/4885EPHX2 4690/4885HSD11B1 4746/4885
US-10202388-B2 Fused-ring compounds, pharmaceutical composition and uses thereof IDO1, IDO2, TDO2 KMT2A 667/4885EPHX2 1124/4885HSD11B1 196/4885
US-20110086405-A1 METHOD FOR PRODUCING HYDROXYLATED ADAMANTANE USING CYTOCHROME P450 CYP3A5, CYP1A2, POR KMT2A 2915/4885EPHX2 88/4885HSD11B1 105/4885
US-20180022752-A1 FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF IDO1, IDO2, TDO2 KMT2A 667/4885EPHX2 1124/4885HSD11B1 196/4885
US-20170233386-A1 Compounds Which Have a Protective Activity with Respect to the Action of Toxins and of Viruses with an Intracellular Mode of Action HAVCR2, MAVS, ANTXR2 KMT2A 4212/4885EPHX2 4690/4885HSD11B1 4746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.