Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15053282 | 1.00 | HMGCR (0.32) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL3621930 | 0.84 | PTGS1 (0.31) | PTGS1AKR1C3 | |
| SCHEMBL1782330 | 0.84 | PKM (0.31) | — | |
| SCHEMBL1782332 | 0.84 | PKM (0.31) | — | |
| SCHEMBL1469906 | 0.84 | PTGS1 (0.31) | PTGS1AKR1C3 | |
| SCHEMBL7717936 | 0.82 | HMGCR (0.32) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL9577435 | 0.82 | HMGCR (0.32) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7120511 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL7120506 | 0.80 | — | — | |
| SCHEMBL6026609 | 0.79 | PTGS1 (0.31) | ALDH1A1PTGS1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569639-B1 | SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS | JOHNSON & JOHNSON VISION CARE (US) | 2025-09-24 | — | — | EP | disclosed |
| EP-2794723-B2 | SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS | JOHNSON & JOHNSON VISION CARE (US) | 2025-06-04 | — | — | EP | disclosed |
| EP-3181614-B9 | SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY | JOHNSON & JOHNSON VISION CARE (US) | 2022-10-05 | — | — | EP | disclosed |
| EP-4011940-A1 | SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY | Johnson & Johnson Vision Care, Inc. (US) | 2022-06-15 | — | — | EP | disclosed |
| EP-3181614-B1 | SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY | JOHNSON & JOHNSON VISION CARE (US) | 2022-03-30 | — | — | EP | disclosed |
| EP-2794727-B2 | IONIC SILICONE HYDROGELS | JOHNSON & JOHNSON VISION CARE (US) | 2020-10-28 | — | — | EP | disclosed |
| EP-3569639-A1 | SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS | Johnson & Johnson Vision Care Inc. (US) | 2019-11-20 | — | — | EP | disclosed |
| EP-2794723-B9 | SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS | JOHNSON & JOHNSON VISION CARE (US) | 2019-11-20 | — | — | EP | disclosed |
| US-10353115-B2 | Silicone hydrogels comprising N-vinyl amides and hydroxyalkyl (meth)acrylates or (meth)acrylamides | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| EP-2794723-B1 | SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS | JOHNSON & JOHNSON VISION CARE (US) | 2019-04-24 | — | — | EP | disclosed |
| EP-2794727-A1 | IONIC SILICONE HYDROGELS | Johnson & Johnson Vision Care Inc. (US) | 2014-10-29 | — | — | EP | disclosed |
| US-20140031447-A1 | SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140024791-A1 | SILICONE HYDROGELS COMPRISING N-VINYL AMIDES AND HYDROXYALKYL (METH)ACRYLATES OR (METH)ACRYLAMIDES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-01-23 | — | — | US | disclosed |
| US-20130217620-A1 | IONIC SILICONE HYDROGELS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| US-20130172440-A1 | SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130168617-A1 | IONIC SILICONE HYDROGELS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| WO-2013096597-A1 | SILICONE HYDROGELS COMPRISING N-VINYL AMIDES AND HYDROXYALKYL (METH)ACRYLATES OR (METH)ACRYLAMIDES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013096587-A1 | SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013096600-A1 | SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013096604-A1 | IONIC SILICONE HYDROGELS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217620-A1 | IONIC SILICONE HYDROGELS | HACD2, IGFBP2, IGFBP6 | HMGCR 1484/4885CHRM1 1697/4885TBXA2R 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.