SCHEMBL1505430

SCHEMBL1505430

COc1cc(NS(=O)(=O)c2ccc(C)cc2)c2ncccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 1.00
TDP1 Q9NUW8 6/20 1.00
MEN1 O00255 5/20 1.00
LMNA P02545 2/20 1.00
MAPT P10636 2/20 1.00
AGTR1 P30556 2/20 1.00
NPSR1 Q6W5P4 2/20 1.00
TP53 P04637 1/20 1.00
HPGD P15428 1/20 1.00
TSHR P16473 1/20 1.00
CXCR2 P25025 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
CKS1B P61024 4/20 0.85
SKP2 Q13309 4/20 0.85
SLC40A1 Q9NP59 10/20 0.82
POLB P06746 1/20 0.79
NFKBIA P25963 3/20 0.71
RELA Q04206 2/20 0.71
MITF O75030 1/20 0.67
S1PR4 O95977 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29575795 1.00 KMT2A (1.00) KMT2ATDP1MEN1LMNAMAPT
SCHEMBL13633886 0.93 MEN1 (1.00) KMT2ATDP1MEN1LMNAMAPT
SCHEMBL17506531 0.92 CKS1B (1.00) KMT2ATDP1MEN1LMNAMAPT
SCHEMBL7197593 0.90 SLC40A1 (1.00) KMT2ATDP1MEN1LMNAMAPT
SCHEMBL4489851 0.89 MEN1 (0.84) KMT2ATDP1MEN1LMNAMAPT
SCHEMBL22111633 0.89 MEN1 (0.84) KMT2ATDP1MEN1LMNAMAPT
SCHEMBL17506539 0.88 KMT2A (0.79) KMT2ATDP1MEN1LMNAMAPT
SCHEMBL22076984 0.88 MEN1 (1.00) KMT2ATDP1MEN1LMNAMAPT
SCHEMBL4472564 0.86 MEN1 (0.79) KMT2ATDP1MEN1LMNAMAPT
SCHEMBL6688368 0.86 SLC40A1 (0.85) KMT2ATDP1MEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116884510-B Constant potential auxiliary electrochemical catalyst model 南通大学 2025-05-02 CN claimed
CN-114555782-B Pancreatic endocrine progenitor cells and uses thereof 中国科学院分子细胞科学卓越创新中心 2024-06-07 CN claimed
CN-116884510-A Constant potential auxiliary electrochemical catalyst model 南通大学 2023-10-13 CN claimed
CN-114444550-B Structured data analysis method and device, electronic equipment and storage medium 中国人民解放军火箭军工程大学 2022-07-29 CN claimed
CN-114555782-A Pancreatic endocrine progenitor cells and uses thereof 中国科学院分子细胞科学卓越创新中心 2022-05-27 CN claimed
CN-114444550-A Structured data analysis method and device, electronic equipment and storage medium 中国人民解放军火箭军工程大学 2022-05-06 CN claimed
US-20210041362-A1 METHOD FOR CALIBRATING FLUORESCENT PLATE READERS PLEXBIO CO LTD (TW) 2021-02-11 US claimed
US-20180071238-A1 Compositions and Methods for Traumatized Tissues Using Zinc Chelators OHIO UNIVERSITY (US) 2018-03-15 US claimed
WO-2016164685-A1 COMPOSITIONS AND METHODS FOR TRAUMATIZED TISSUES USING ZINC CHELATORS OHIO UNIVERSITY (US) 2016-10-13 WO claimed
WO-2016164488-A1 FLOW CYTOMETRY BASED ASSAY FOR BIOAVAILABLE ZINC SHRINERS HOSPITAL FOR CHILDREN (US) 2016-10-13 WO claimed
US-7901852-B2 Metrology of bilayer photoresist processes FREESCALE SEMICONDUCTOR, INC. (US) 2011-03-08 US claimed
US-20090220895-A1 Metrology of bilayer photoresist processes FREESCALE SEMICONDUCTOR, INC. 2009-09-03 US claimed
US-20090203749-A1 AGENT FOR CONTROL OF DEGRANULATION REACTION AND CYTOKINE PRODUCTION RIKEN (JP) 2009-08-13 US claimed
US-20090054316-A1 AGENT FOR CONTROL OF FUNCTION OF ANTIGEN-PRESENTING CELL RIKEN (JP) 2009-02-26 US claimed
EP-1854483-A1 AGENT FOR CONTROL OF FUNCTION OF ANTIGEN-PRESENTING CELL Riken (JP) 2007-11-14 EP claimed
EP-1854482-A1 AGENT FOR CONTROL OF DEGRANULATION REACTION AND CYTOKINE PRODUCTION Riken (JP) 2007-11-14 EP claimed
US-20030211454-A1 Detection reagent GE HEALTHCARE UK LIMITED (GB) 2003-11-13 US claimed
WO-1997009976-A2 METHOD OF REDUCING NEUROTOXIC INJURY WITH ZINC CHELATORS WASHINGTON UNIVERSITY (CH) 1997-03-20 WO claimed
WO-2026104587-A1 CYCLIC BORONIC ACID ESTERS USEFUL AS ADJUVANTS IN THE TREATMENT OF BACTERIAL INFECTIONS ADJUTEC PHARMA AS (NO) 2026-05-21 WO disclosed
US-5459276-A Chelate compounds for fluorescence MOLECULAR PROBES, INC. (US) 1995-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211454-A1 Detection reagent DDT, DLD, DLK1 KMT2A 3528/4885TDP1 1896/4885MEN1 416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.