Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21679933 | 0.80 | CES2 (0.52) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL123450 | 0.79 | CES2 (0.54) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL13176937 | 0.79 | HSD17B1 (0.52) | CES2CA1CA2LMNAMAPT | |
| SCHEMBL5382720 | 0.79 | ALDH1A1 (0.54) | CES2CES1GSK3BLMNAMAPT | |
| SCHEMBL27720360 | 0.77 | CES2 (0.52) | CES2CES1CA1CA2MAPT | |
| SCHEMBL2080074 | 0.77 | CES2 (0.52) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL17591087 | 0.77 | MAPT (0.48) | CA1CA2LMNAMAPTRAB9A | |
| SCHEMBL1380046 | 0.77 | CES2 (0.52) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL10888312 | 0.77 | CES2 (0.65) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL536908 | 0.77 | MEN1 (0.48) | CES2CES1CA1CA2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125919-A | Preparation method of conjugated triene compound | 华南理工大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-112441997-B | Method for synthesizing alpha- (2-tetrahydrofuryl) -acetophenone compound | 浙江工业大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-112441997-A | Method for synthesizing alpha- (2-tetrahydrofuryl) -acetophenone compound | 浙江工业大学 | 2021-03-05 | — | — | CN | disclosed |
| US-9120721-B2 | Method of preparing chiral ketones from aldehydes | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-09-01 | — | — | US | disclosed |
| US-9120721-B2 | Method of preparing chiral ketones from aldehydes | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-09-01 | — | — | US | disclosed |
| US-9120721-B2 | Method of preparing chiral ketones from aldehydes | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-09-01 | — | — | US | disclosed |
| US-20140309459-A1 | METHOD OF PREPARING CHIRAL KETONES FROM ALDEHYDES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-10-16 | — | — | US | disclosed |
| US-20140309459-A1 | METHOD OF PREPARING CHIRAL KETONES FROM ALDEHYDES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-10-16 | — | — | US | disclosed |
| US-20140309459-A1 | METHOD OF PREPARING CHIRAL KETONES FROM ALDEHYDES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-10-16 | — | — | US | disclosed |
| WO-2013095301-A1 | METHOD OF PREPARING CHIRAL KETONES FROM ALDEHYDES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309459-A1 | METHOD OF PREPARING CHIRAL KETONES FROM ALDEHYDES | CBR1, CBR3, AKR1C3 | CES2 611/4885CES1 391/4885CA1 532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.