SCHEMBL150557

SCHEMBL150557

C=CC(=O)NC(O)(O)CCO

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23646842 0.80 TSHR (0.41) TSHRALDH1A1MAPK1TDP1CYP3A4
SCHEMBL20467953 0.77 MEN1 (0.53) TSHRALDH1A1MAPK1TDP1CYP3A4
SCHEMBL7037814 0.77 ALDH1A1 (0.38) TSHRALDH1A1MAPK1TDP1CYP3A4
SCHEMBL3235326 0.75 ALDH1A1 (0.44) TSHRALDH1A1MAPK1TDP1CYP3A4
SCHEMBL105093 0.74 ALDH1A1 (0.50) TSHRALDH1A1MAPK1TDP1CYP3A4
SCHEMBL28502035 0.74 ALDH1A1 (0.35) TSHRALDH1A1MAPK1TDP1CYP3A4
SCHEMBL9328483 0.73 ALDH1A1 (0.42) TSHRALDH1A1MAPK1TDP1CYP3A4
SCHEMBL4374138 0.73 ALDH1A1 (0.42) TSHRALDH1A1MAPK1TDP1CYP3A4
SCHEMBL21728872 0.72 ALDH1A1 (0.39) TSHRALDH1A1MAPK1TDP1CYP3A4
SCHEMBL27961654 0.71 ALDH1A1 (0.43) TSHRALDH1A1MAPK1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012198-B2 Method for orthopoxvirus production and purification TRANSGENE S.A. (FR) 2015-04-21 US disclosed
US-20140073033-A1 METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION TRANSGENE S.A. (FR) 2014-03-13 US disclosed
US-8609392-B2 Method for orthopoxvirus production and purification TRANSGENE S.A. (FR) 2013-12-17 US disclosed
US-20120190100-A1 ENZYMATIC COMPOSITION FOR THE DIGESTION OF CHICKEN EMBRYOS Transgene AS (FR) 2012-07-26 US disclosed
EP-2456461-A1 ENZYMATIC COMPOSITION FOR THE DIGESTION OF CHICKEN EMBRYOS Transgene SA (FR) 2012-05-30 EP disclosed
EP-2429580-A1 METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION Transgene SA (FR) 2012-03-21 EP disclosed
US-20120058539-A1 METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION TRANSGENE S.A. (FR) 2012-03-08 US disclosed
WO-2011009613-A1 ENZYMATIC COMPOSITION FOR THE DIGESTION OF CHICKEN EMBRYOS TRANSGENE SA (FR) 2011-01-27 WO disclosed
WO-2010130753-A1 METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION TRANSGENE SA (FR) 2010-11-18 WO disclosed
US-7264958-B1 Method for obtaining a purified viral preparation TRANSGENE, S.A. (FR) 2007-09-04 US disclosed