SCHEMBL105093

SCHEMBL105093

C=CC(=O)NCC(O)(O)NC(=O)C=C

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
TSHR P16473 2/20 0.50
MAPK1 P28482 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TGM2 P21980 2/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.31
CNR1 P21554 4/20 0.31
CNR2 P34972 4/20 0.31
TRPA1 O75762 1/20 0.31
TRPV1 Q8NER1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2319044 0.79 TSHR (0.56) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL5672331 0.78 ALDH1A1 (0.51) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL6566267 0.76 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL23064184 0.76 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL16205191 0.74 ALDH1A1 (0.56) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL150557 0.74 TSHR (0.39) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL138083 0.73 ALDH1A1 (0.54) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL1695817 0.73 TSHR (0.54) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL4789482 0.73 TSHR (0.54) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL22490941 0.72 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1TDP1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12534663-B2 Re-crosslinkable hyper-branched polymer gels based on a transamidation reaction THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2026-01-27 US claimed
US-12247156-B2 Re-crosslinkable particle for conformance control and temporary plugging THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2025-03-11 US claimed
US-20240132771-A1 RE-CROSSLINKABLE HYPER-BRANCHED POLYMER GELS BASED ON A TRANSMIDATION REACTION THE CURATORS OF THE UNIVERSITY OF MISSOURI 2024-04-25 US claimed
EP-4240804-A1 RE-CROSSLINKABLE HYPER-BRANCHED POLYMER GELS BASED ON A TRANSMIDATION REACTION The Curators Of The University Of Missouri (US) 2023-09-13 EP claimed
CN-112839994-B A kind ofFor controlling CO 2 Consistency and CO rejection 2 Leaky re-crosslinked particulate gels 密苏里大学 2023-03-28 CN claimed
US-20230055352-A1 RE-CROSSLINKABLE PARTICLE FOR CONFORMANCE CONTROL AND TEMPORARY PLUGGING THE CURATORS OF THE UNIVERSITY OF MISSOURI 2023-02-23 US claimed
US-20220202951-A1 LIGHT-TRIGGERABLE NANOPARTICLE LIBRARY OF FORMULATIONS FOR THE CONTROLLED RELEASE OF RNAS UNIVERSIDADE DE COIMBRA (PT) 2022-06-30 US claimed
WO-2022098411-A1 RE-CROSSLINKABLE HYPER-BRANCHED POLYMER GELS BASED ON A TRANSMIDATION REACTION THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2022-05-12 WO claimed
EP-3969049-A1 A LIGHT-TRIGGERABLE NANOPARTICLE LIBRARY OF FORMULATIONS FOR THE CONTROLLED RELEASE OF RNAS Universidade de Coimbra (PT) 2022-03-23 EP claimed
US-11135565-B2 Metal organic framework (MOF) composite materials, methods, and uses thereof UTI LIMITED PARTNERSHIP (CA) 2021-10-05 US claimed
EP-0637328-B1 POLYETHERAMIDOAMINE SUPERABSORBENT HYDROGELS ANGELINI RICERCHE SPA (IT) 1997-07-30 EP claimed
US-5606012-A COMPLEXING WITH HEPARIN; MEDICAL EQUIPMENT SOCIETA' CONSORTILE RICERCHE ANGELINI S.P.A. (IT) 1997-02-25 US claimed
US-5571890-A CROSSLINKABLE COMPOSITIONS WITH MICHAEL NUCLEOPHILIC POLYADDITION SOCIETA CONSORTILE RICERCHE ANGELINI S.P.A. (IT) 1996-11-05 US claimed
EP-0637327-A1 POLYETHERAMIDOAMINE HYDROGELS AS HEPARINIZABLE MATERIALS SOCIETA' CONSORTILE RICERCHE ANGELINI S.p.A (IT) 1995-02-08 EP claimed
EP-0637328-A1 POLYETHERAMIDOAMINE SUPERABSORBENT HYDROGELS. ANGELINI CONSORT RICERCHE (IT) 1995-02-08 EP claimed
US-5321357-A Three-dimensional detection, dosimetry and imaging of an energy field by formation of a polymer in a gel YALE UNIVERSITY (US) 1994-06-14 US claimed
WO-1994003826-A1 DOSIMETRY AND IMAGING OF RADIANT ENERGY BY FORMATION OF A POLYMER IN A GEL YALE UNIVERSITY (US) 1994-02-17 WO claimed
WO-1993021256-A1 POLYETHERAMIDOAMINE SUPERABSORBENT HYDROGELS SOCIETA' CONSORTILE RICERCHE ANGELINI S.P.A. (IT) 1993-10-28 WO claimed
WO-1993021257-A1 POLYETHERAMIDOAMINE HYDROGELS AS HEPARINIZABLE MATERIALS SOCIETA' CONSORTILE RICERCHE ANGELINI S.P.A. (IT) 1993-10-28 WO claimed
US-4840756-A PHOTOPOLYMERIZATION OF ACRYLAMIDE; CONTROLLED POROSITY E. I. DU PONT NEMOURS AND COMPANY (US) 1989-06-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534663-B2 Re-crosslinkable hyper-branched polymer gels based on a transamidation reaction PHOSPHO1, TERT, AS3MT ALDH1A1 2931/4885TSHR 488/4885MAPK1 3808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.