Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15079144 | 0.89 | ALDH1A1 (0.46) | LMNAALDH1A1MAPK1L3MBTL1KDM4E | |
| Trifluoromethanesulfonic Acid SCHEMBL15056761 | 0.85 | LMNA (0.42) | LMNAALDH1A1MAPK1L3MBTL1CA1 | |
| SCHEMBL15056282 | 0.83 | LMNA (0.39) | LMNAALDH1A1MAPK1L3MBTL1CA1 | |
| SCHEMBL15056762 | 0.78 | LMNA (0.36) | LMNAALDH1A1MAPK1L3MBTL1MAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL7043963 | 0.75 | CA1 (0.40) | LMNAALDH1A1MAPK1L3MBTL1CA1 | |
| SCHEMBL15079140 | 0.71 | ALDH1A1 (0.49) | LMNAALDH1A1MAPK1L3MBTL1NPC1 | |
| Bromide SCHEMBL15056150 | 0.69 | POLB (0.57) | LMNAALDH1A1MAPK1KDM4ENPC1 | |
| Trifluoromethanesulfonic Acid SCHEMBL2844529 | 0.69 | ALOX5 (0.38) | LMNAALDH1A1CA1CA2GAA | |
| SCHEMBL15628152 | 0.68 | ALDH1A1 (0.54) | LMNAALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL16260122 | 0.68 | ALDH1A1 (0.58) | LMNAALDH1A1MAPK1L3MBTL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140349297-A1 | FLUORESCENT DYES BASED ON ACRIDINE AND ACRIDINIUM DERIVATIVES | ALMAC SCIENCES (SCOTLAND) LIMITED (GB) | 2014-11-27 | — | — | US | disclosed |
| EP-2795324-A1 | FLUORESCENT DYES BASED ON ACRIDINE AND ACRIDINIUM DERIVATIVES | Almac Sciences (Scotland) Limited (GB) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013093481-A1 | FLUORESCENT DYES BASED ON ACRIDINE AND ACRIDINIUM DERIVATIVES | ALMAC SCIENCES (SCOTLAND) LIMITED (GB) | 2013-06-27 | — | — | WO | disclosed |