Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Nitroaniline SCHEMBL29058965 | 0.84 | ALDH1A1 (0.58) | SLC7A5NPC1SMN1; SMN2CYP3A4MAPT | |
| Nitrobenzene SCHEMBL9768008 | 0.80 | ALDH1A1 (0.55) | SLC7A5NPC1SMN1; SMN2SLC1A3SLC1A2 | |
| P-Nitrophenol SCHEMBL4805916 | 0.77 | SLC1A3 (0.50) | SLC7A5MAPTSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7080519 | 0.77 | NPC1 (0.46) | NPC1SMN1; SMN2CYP3A4MAPTGRM8 | |
| Urea SCHEMBL3678424 | 0.77 | SMN1; SMN2 (0.63) | NPC1SMN1; SMN2CYP3A4MAPTTSHR | |
| SCHEMBL65293 | 0.76 | CYP19A1 (0.62) | NPC1SMN1; SMN2CYP3A4MAPTTSHR | |
| Valine SCHEMBL10510346 | 0.76 | SLC1A3 (0.49) | SLC7A5NPC1SMN1; SMN2MAPTSLC1A3 | |
| Phenylglycine SCHEMBL16340621 | 0.75 | ALDH1A1 (0.45) | NPC1SMN1; SMN2CYP3A4MAPTGRM8 | |
| Valine SCHEMBL8367874 | 0.74 | SLC7A5 (0.71) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Valine SCHEMBL1487681 | 0.74 | SLC7A5 (0.71) | SLC7A5SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794621-B1 | NOVEL ORGANOSILICA COMPOUNDS | UNIV GENT (BE) | 2018-09-26 | — | — | EP | disclosed |
| US-9181282-B2 | Organosilica compounds | UNIVERSITEIT GENT (BE) | 2015-11-10 | — | — | US | disclosed |
| US-20150005525-A1 | NOVEL ORAGNOSILICA COMPOUNDS | UNIVERSITEIT GENT (BE) | 2015-01-01 | — | — | US | disclosed |
| EP-2794621-A1 | NOVEL ORGANOSILICA COMPOUNDS | Universiteit Gent (BE) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013093022-A1 | NOVEL ORGANOSILICA COMPOUNDS | UNIVERSITEIT GENT (BE) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005525-A1 | NOVEL ORAGNOSILICA COMPOUNDS | ORC3, ORMDL3, OR10J3 | SLC7A5 813/4885NPC1 2957/4885SMN1; SMN2 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.