SCHEMBL1505769

SCHEMBL1505769

CC(Nc1cncs1)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.37
ALDH1A1 P00352 3/20 0.36
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
CA14 Q9ULX7 2/20 0.34
HPGD P15428 1/20 0.34
MCL1 Q07820 2/20 0.33
BCL2 P10415 1/20 0.33
CSF1R P07333 2/20 0.33
LRRK2 Q5S007 1/20 0.32
KMT2A Q03164 2/20 0.32
PIK3CD O00329 1/20 0.32
CD38 P28907 1/20 0.32
LMNA P02545 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1505770 1.00 HDAC1 (0.37) HDAC1ALDH1A1CA12CA1CA2
SCHEMBL26118022 0.78 HDAC1 (0.35) HDAC1CA2CSF1RLRRK2KMT2A
SCHEMBL26118027 0.78 HDAC1 (0.35) HDAC1CA2CSF1RLRRK2KMT2A
SCHEMBL4955773 0.71
SCHEMBL15577218 0.69
Bicarbonate SCHEMBL28121604 0.69 KMT2A (0.34) HDAC1CSF1RKMT2ACD38TDP1
SCHEMBL41619 0.69 GAA (0.53) ALDH1A1HPGDKMT2ALMNATDP1
SCHEMBL41618 0.69 GAA (0.53) ALDH1A1HPGDKMT2ALMNATDP1
SCHEMBL199861 0.69 GAA (0.53) ALDH1A1HPGDKMT2ALMNATDP1
Benzene SCHEMBL27553763 0.69 GAA (0.53) ALDH1A1HPGDKMT2ALMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823223-A Apelin peptide energy macrocycle and application thereof SOCPRA健康与人文科学有限公司 2025-04-15 CN disclosed
EP-4448547-A1 APELINERGIC MACROCYCLES AND USES THEREOF Socpra Sciences Santé Et Humaines S.E.C. (CA) 2024-10-23 EP disclosed
CN-118829646-A Apelin peptide energy macrocycle and application thereof SOCPRA健康与人文科学有限公司 2024-10-22 CN disclosed
US-20240343761-A1 APELINERGIC MACROCYCLES AND USES THEREOF SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2024-10-17 US disclosed
US-20240082344-A1 METHOD OF TREATING PRADER-WILLI SYNDROME FERRING B.V. (NL) 2024-03-14 US disclosed
WO-2024011333-A1 METHOD OF TREATING SKELETAL MUSCLE STEM CELL PATHOLOGIC DYSFUNCTION SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2024-01-18 WO disclosed
EP-3666258-B1 METHOD OF TREATING PRADER-WILLI SYNDROME FERRING BV (NL) 2023-11-15 EP disclosed
WO-2023108291-A9 APELINERGIC MACROCYCLES AND USES THEREOF SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2023-09-28 WO disclosed
WO-2023108291-A1 APELINERGIC MACROCYCLES AND USES THEREOF SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2023-06-22 WO disclosed
CN-112773765-A Methods of treating prader-willi syndrome 辉凌公司 2021-05-11 CN disclosed
US-20200129584-A1 METHOD OF TREATING PRADER-WILLI SYNDROME FERRING B.V. (NL) 2020-04-30 US disclosed
US-10441627-B2 Method of treating prader-willi syndrome FERRING B.V. (NL) 2019-10-15 US disclosed
US-20170326200-A1 Method of Treating Prader-Willi Syndrome FERRING B.V. (NL) 2017-11-16 US disclosed
EP-3193907-A1 METHOD OF TREATING PRADER-WILLI SYNDROME Ferring BV (NL) 2017-07-26 EP disclosed
CN-102656183-B Oxytocin receptor agonist FERRING B.V. (NL) 2016-03-30 CN disclosed
WO-2016044131-A1 METHOD OF TREATING PRADER-WILLI SYNDROME FERRING B.V. (NL) 2016-03-24 WO disclosed
US-8748564-B2 Oxytocin receptor agonists FERRING B.V. (NL) 2014-06-10 US disclosed
EP-2491052-A2 OXYTOCIN RECEPTOR AGONISTS Ferring International Center S.A. (CH) 2012-08-29 EP disclosed
US-20120214733-A1 OXYTOCIN RECEPTOR AGONISTS FERRING INTERNATIONAL CENTER S.A. (CH) 2012-08-23 US disclosed
WO-2011035330-A2 OXYTOCIN RECEPTOR AGONISTS FERRING INTERNATIONAL CENTER S.A. (CH) 2011-03-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10441627-B2 Method of treating prader-willi syndrome OXTR, MC2R, AVPR2 HDAC1 644/4885ALDH1A1 3379/4885CA12 3252/4885
US-20240343761-A1 APELINERGIC MACROCYCLES AND USES THEREOF APLNR, AP3D1, AP3B1 HDAC1 1999/4885ALDH1A1 2222/4885CA12 1670/4885
US-20240082344-A1 METHOD OF TREATING PRADER-WILLI SYNDROME OXTR, MC2R, AVPR2 HDAC1 644/4885ALDH1A1 3379/4885CA12 3252/4885
US-20170326200-A1 Method of Treating Prader-Willi Syndrome OXTR, MC2R, AVPR2 HDAC1 644/4885ALDH1A1 3379/4885CA12 3252/4885
US-20200129584-A1 METHOD OF TREATING PRADER-WILLI SYNDROME OXTR, MC2R, AVPR2 HDAC1 644/4885ALDH1A1 3379/4885CA12 3252/4885
US-20120214733-A1 OXYTOCIN RECEPTOR AGONISTS OXTR, PRLHR, AVPR1A HDAC1 2609/4885ALDH1A1 2418/4885CA12 4494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.