Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
| ▸ | NOS2 | P35228 | 3/20 | 0.37 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15058260 | 1.00 | NOS1 (0.37) | NOS1NOS2CAMK2ACYP1A2CYP2D6 | |
| SCHEMBL15058972 | 0.95 | NOS1 (0.39) | NOS1NOS2CAMK2ACYP1A2CYP2D6 | |
| SCHEMBL15058973 | 0.95 | NOS1 (0.39) | NOS1NOS2CAMK2ACYP1A2CYP2D6 | |
| SCHEMBL10537802 | 0.80 | CAMK2A (0.38) | CAMK2ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15058647 | 0.77 | NOS1 (0.31) | NOS1NOS2 | |
| SCHEMBL15058646 | 0.77 | NOS1 (0.31) | NOS1NOS2 | |
| SCHEMBL9813664 | 0.75 | CAMK2A (0.37) | CAMK2ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1133545 | 0.74 | NOS1 (0.52) | NOS1NOS2NOS3 | |
| SCHEMBL15058282 | 0.73 | NOS1 (0.33) | NOS1NOS2NOS3 | |
| SCHEMBL15058284 | 0.73 | NOS1 (0.33) | NOS1NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794564-B1 | STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-24 | — | — | EP | disclosed |
| US-9131688-B2 | Strigolactam derivatives as plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-15 | — | — | US | disclosed |
| US-9131688-B2 | Strigolactam derivatives as plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-15 | — | — | US | disclosed |
| US-9131688-B2 | Strigolactam derivatives as plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-15 | — | — | US | disclosed |
| US-20140336052-A1 | STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-13 | — | — | US | disclosed |
| US-20140336052-A1 | STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-13 | — | — | US | disclosed |
| US-20140336052-A1 | STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-13 | — | — | US | disclosed |
| EP-2794564-A1 | STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | Syngenta Participations AG (CH) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013092430-A1 | STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336052-A1 | STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | AREG, GHITM, GRK6 | NOS1 510/4885NOS2 762/4885CAMK2A 1679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.