Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15058647 | 1.00 | NOS1 (0.31) | NOS1NOS2ELANEEPHX1 | |
| SCHEMBL15058284 | 0.96 | NOS1 (0.33) | NOS1NOS2ELANEEPHX1 | |
| SCHEMBL15058282 | 0.96 | NOS1 (0.33) | NOS1NOS2ELANEEPHX1 | |
| SCHEMBL15058260 | 0.77 | NOS1 (0.37) | NOS1NOS2 | |
| SCHEMBL15058261 | 0.77 | NOS1 (0.37) | NOS1NOS2 | |
| SCHEMBL15058973 | 0.73 | NOS1 (0.39) | NOS1NOS2 | |
| SCHEMBL15058972 | 0.73 | NOS1 (0.39) | NOS1NOS2 | |
| SCHEMBL19768596 | 0.69 | TP53 (0.34) | NOS1NOS2EPHX1 | |
| SCHEMBL17964282 | 0.69 | NOS1 (0.34) | NOS1NOS2EPHX1 | |
| SCHEMBL19768571 | 0.69 | BTK (0.31) | NOS1NOS2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794564-B1 | STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-24 | — | — | EP | disclosed |
| EP-2794564-B1 | STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-24 | — | — | EP | disclosed |
| US-9131688-B2 | Strigolactam derivatives as plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-15 | — | — | US | disclosed |
| US-9131688-B2 | Strigolactam derivatives as plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-15 | — | — | US | disclosed |
| US-20140336052-A1 | STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-13 | — | — | US | disclosed |
| US-20140336052-A1 | STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-13 | — | — | US | disclosed |
| EP-2794564-A1 | STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | Syngenta Participations AG (CH) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013092430-A1 | STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336052-A1 | STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | AREG, GHITM, GRK6 | NOS1 510/4885NOS2 762/4885ELANE 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.