SCHEMBL1505828

SCHEMBL1505828

Cc1ccc(-c2c3ccccc3cc3ccccc23)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.55
GPR84 Q9NQS5 1/20 0.51
ACHE P22303 1/20 0.49
CYP1A2 P05177 5/20 0.48
CYP2A6 P11509 2/20 0.48
TDP1 Q9NUW8 2/20 0.43
ALDH1A1 P00352 4/20 0.42
HPGD P15428 3/20 0.42
HSD17B10 Q99714 2/20 0.42
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
ADORA2A P29274 1/20 0.41
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6339329 0.89 ALOX5 (0.46) ALOX5GPR84ACHECYP1A2CYP2A6
SCHEMBL13222607 0.86 ALOX5 (0.44) ALOX5GPR84ACHECYP1A2CYP2A6
SCHEMBL14004024 0.86 GPR84 (0.46) ALOX5GPR84ACHECYP1A2CYP2A6
SCHEMBL7261308 0.86 CYP1A2 (0.59) ALOX5GPR84ACHECYP1A2CYP2A6
SCHEMBL9958670 0.85 CYP1A2 (0.47) ALOX5GPR84ACHECYP1A2CYP2A6
SCHEMBL26763751 0.84 CYP1A2 (0.50) ALOX5GPR84ACHECYP1A2CYP2A6
SCHEMBL30742831 0.84 ACHE (0.57) ACHETDP1ALDH1A1HPGDKDM4E
SCHEMBL27950152 0.84 ALOX5 (0.59) ALOX5ACHECYP1A2CYP2A6TDP1
SCHEMBL3477351 0.84 ACHE (0.57) ACHETDP1ALDH1A1HPGDKDM4E
SCHEMBL14577471 0.83 ALOX5 (0.41) ALOX5GPR84ACHECYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113860984-A Magnesium-activated ligand-promoted chromium-catalyzed polycyclic aromatic hydrocarbon and olefin regioselective hydrogenation method 延安大学 2021-12-31 CN disclosed
CN-107216229-B A kind of method of chromic salts/methyl-magnesium-bromide selective catalytic hydrogenation polycyclic aromatic hydrocarbon 四川大学 2019-07-09 CN disclosed
CN-107235818-B Method based on cobalt salt selective catalytic hydrogenation polycyclic aromatic hydrocarbon 四川大学 2019-07-09 CN disclosed
CN-107235818-A Method based on cobalt salt selective catalytic hydrogenation polycyclic aromatic hydrocarbon 四川大学 2017-10-10 CN disclosed
CN-107216229-A A kind of method of chromic salts/methyl-magnesium-bromide selective catalytic hydrogenation polycyclic aromatic hydrocarbon 四川大学 2017-09-29 CN disclosed
CN-101153036-B Organic light-emitting compound and organic light-emitting element comprising the same SAMSUNG MOBILE DISPLAY CO LTD 2012-10-03 CN disclosed
US-7901793-B2 Organic light-emitting compound and organic light-emitting device containing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-03-08 US disclosed
CN-101153036-A Organic light-emitting compound and organic light-emitting element comprising the same SAMSUNG SDI CO LTD (KR) 2008-04-02 CN disclosed
US-20070072002-A1 Organic light-emitting compound and organic light-emitting device containing the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-03-29 US disclosed
US-5597841-A 2-saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof STERLING WINTHROP, INC. (US) 1997-01-28 US disclosed
US-5512589-A TREATING DEGENERATIVE DISEASES STERLING WINTHROP INC. (US) 1996-04-30 US disclosed
US-5306818-A Treating degenerative diseases such as emphysema, rheumatoid arthritis and pancreatitis STERLING WINTHROP INC. (US) 1994-04-26 US disclosed
US-5250696-A Treatment of degenerative diseases STERLING WINTHROP INC. (US) 1993-10-05 US disclosed
US-5128339-A Emphysema, rheumatoid arthritis, pancreatitis STERLING WINTHROP INC. (US) 1992-07-07 US disclosed