Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.66 |
| ▸ | NOS1 | P29475 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15058732 | 1.00 | NOS3 (0.66) | NOS3NOS1LMNAHTTNPC1 | |
| SCHEMBL15058733 | 1.00 | NOS3 (0.66) | NOS3NOS1LMNAHTTNPC1 | |
| SCHEMBL15322209 | 0.87 | NOS3 (0.51) | NOS3NOS1LMNANPC1RAB9A | |
| SCHEMBL15322213 | 0.87 | NOS3 (0.51) | NOS3NOS1LMNANPC1RAB9A | |
| SCHEMBL7700455 | 0.79 | LMNA (0.56) | NOS3NOS1LMNAHTTNPC1 | |
| SCHEMBL10298337 | 0.79 | LMNA (0.56) | NOS3NOS1LMNAHTTNPC1 | |
| SCHEMBL22920960 | 0.78 | NOS3 (0.42) | NOS3NOS1LMNAHTTNPC1 | |
| SCHEMBL14378468 | 0.74 | LMNA (0.51) | NOS3NOS1LMNAHTTNPC1 | |
| SCHEMBL22782643 | 0.74 | LMNA (0.51) | NOS3NOS1LMNAHTTNPC1 | |
| SCHEMBL6816473 | 0.74 | NPC1 (0.54) | NOS3NOS1LMNAHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334275-B2 | Processes for preparing indoles | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-05-10 | — | — | US | disclosed |
| US-20150005494-A1 | PROCESSES FOR PREPARING INDOLES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-01-01 | — | — | US | disclosed |
| WO-2013095304-A1 | PROCESSES FOR PREPARING INDOLES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005494-A1 | PROCESSES FOR PREPARING INDOLES | IDO1, INMT, IDO2 | NOS3 382/4885NOS1 358/4885LMNA 2411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.