Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 6/20 | 0.61 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.58 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 2/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | PNP | P00491 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | KRAS | P01116 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011969 | 0.93 | HINT1 (0.59) | HINT1TAS1R3TAS1R1NT5EGSK3A | |
| SCHEMBL11910704 | 0.92 | HINT1 (0.58) | HINT1TAS1R3TAS1R1NT5EGSK3A | |
| SCHEMBL14559269 | 0.92 | HINT1 (0.58) | HINT1TAS1R3TAS1R1NT5EGSK3A | |
| SCHEMBL18179095 | 0.92 | HINT1 (0.58) | HINT1TAS1R3TAS1R1NT5EGSK3A | |
| SCHEMBL15061595 | 0.91 | HINT1 (0.67) | HINT1TAS1R3TAS1R1NT5EGSK3A | |
| SCHEMBL16805371 | 0.90 | HINT1 (0.56) | HINT1TAS1R3TAS1R1NT5EGSK3A | |
| SCHEMBL17211047 | 0.90 | HINT1 (0.56) | HINT1TAS1R3TAS1R1NT5EGSK3A | |
| SCHEMBL31725233 | 0.88 | TAS1R3 (0.74) | HINT1TAS1R3TAS1R1NT5ETGM2 | |
| SCHEMBL26623839 | 0.87 | HINT1 (0.56) | HINT1TAS1R3TAS1R1NT5EGSK3A | |
| SCHEMBL13597930 | 0.87 | HPGD (0.58) | HINT1TAS1R3TAS1R1NT5EGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470801-B2 | Myocardial perfusion imaging methods and compositions | GILEAD SCIENCES, INC. (US) | 2013-06-25 | — | — | US | disclosed |