SCHEMBL5011969

SCHEMBL5011969

CC(=O)O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(=O)[nH]c(N)nc21

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HINT1 P49773 6/20 0.59
TAS1R3 Q7RTX0 1/20 0.58
TAS1R1 Q7RTX1 1/20 0.58
HPGD P15428 2/20 0.56
NT5E P21589 1/20 0.54
GSK3A P49840 2/20 0.53
RPS6KA3 P51812 2/20 0.53
MAPK14 Q16539 2/20 0.53
PNP P00491 2/20 0.51
TGM2 P21980 1/20 0.51
ALDH1A1 P00352 1/20 0.49
TAAR1 Q96RJ0 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15060652 0.93 HINT1 (0.61) HINT1TAS1R3TAS1R1HPGDNT5E
SCHEMBL8205186 0.92 HPGD (0.58) HINT1TAS1R3TAS1R1HPGDNT5E
SCHEMBL13597930 0.92 HPGD (0.58) HINT1TAS1R3TAS1R1HPGDNT5E
SCHEMBL3812199 0.92 HPGD (0.58) HINT1TAS1R3TAS1R1HPGDNT5E
SCHEMBL15061595 0.91 HINT1 (0.67) HINT1TAS1R3TAS1R1NT5EGSK3A
SCHEMBL2582792 0.90 HPGD (0.56) HINT1TAS1R3TAS1R1HPGDNT5E
SCHEMBL12300426 0.89 HPGD (0.61) HINT1TAS1R3TAS1R1HPGDNT5E
SCHEMBL16360143 0.89 HPGD (0.61) HINT1TAS1R3TAS1R1HPGDNT5E
SCHEMBL3713950 0.89 HPGD (0.61) HINT1TAS1R3TAS1R1HPGDNT5E
SCHEMBL18512866 0.89 HPGD (0.61) HINT1TAS1R3TAS1R1HPGDNT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12618064-B2 Acetylated ribonucleic acids and uses thereof HELIX NANOTECHNOLOGIES INC (US) 2026-05-05 US disclosed
US-20250346888-A1 PROMOTER PROXIMAL SEQUENCES AND USES THEREOF FOR RNA MANUFACTURING HELIX NANOTECHNOLOGIES INC (US) 2025-11-13 US disclosed
US-20250270299-A1 METHODS OF USING COMPOSITIONS COMPRISING SBI DOMAINS HELIX NANOTECHNOLOGIES INC 2025-08-28 US disclosed
US-20250129364-A1 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF HELIX NANOTECHNOLOGIES INC 2025-04-24 US disclosed
EP-4519280-A2 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF Helix Nanotechnologies Inc (US) 2025-03-12 EP disclosed
US-12215317-B2 Acetylated ribonucleic acids and uses thereof HELIX NANOTECHNOLOGIES INC (US) 2025-02-04 US disclosed
US-20230383287-A1 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF HELIX NANOTECHNOLOGIES INC 2023-11-30 US disclosed
US-20230383287-A1 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF HELIX NANOTECHNOLOGIES INC 2023-11-30 US disclosed
US-20230383287-A1 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF HELIX NANOTECHNOLOGIES INC 2023-11-30 US disclosed
WO-2023215516-A2 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF HELIX NANOTECHNOLOGIES, INC. (US) 2023-11-09 WO disclosed
WO-2008112826-A1 METHOD AND PROCESS FOR THE PRODUCTION OF MULTI-COATED RECOGNITIVE AND RELEASING SYSTEMS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2008-09-18 WO disclosed
EP-0670845-A1 PROCESS FOR THE PREPARATION OF FLUDARABINE PHOSPHATE FROM GUANOSINE SCHERING AKTIENGESELLSCHAFT (DE) 1995-09-13 EP disclosed
WO-1994012514-A1 PROCESS FOR THE PREPARATION OF FLUDARABINE PHOSPHATE FROM GUANOSINE SCHERING AKTIENGESELLSCHAFT (DE) 1994-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12215317-B2 Acetylated ribonucleic acids and uses thereof NSUN2, NSUN3, ADAR HINT1 757/4885TAS1R3 3515/4885TAS1R1 3915/4885
US-20230383287-A1 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF NSUN2, NSUN3, ADAR HINT1 757/4885TAS1R3 3515/4885TAS1R1 3915/4885
US-12618064-B2 Acetylated ribonucleic acids and uses thereof RNMT, TRDMT1, TRMT1L HINT1 1406/4885TAS1R3 3082/4885TAS1R1 3264/4885
US-20250346888-A1 PROMOTER PROXIMAL SEQUENCES AND USES THEREOF FOR RNA MANUFACTURING RNGTT, NSUN2, CPSF6 HINT1 1377/4885TAS1R3 3931/4885TAS1R1 4355/4885
US-20250270299-A1 METHODS OF USING COMPOSITIONS COMPRISING SBI DOMAINS C1QBP, SSB, SARNP HINT1 396/4885TAS1R3 4781/4885TAS1R1 4777/4885
US-20250129364-A1 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF NSUN2, NSUN3, ADAR HINT1 757/4885TAS1R3 3515/4885TAS1R1 3915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.