Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620922 | 0.86 | — | — | |
| SCHEMBL1966551 | 0.81 | LMNA (0.41) | ALDH1A1 | |
| SCHEMBL23465141 | 0.79 | LMNA (0.34) | — | |
| SCHEMBL31676368 | 0.78 | LMNA (0.38) | — | |
| SCHEMBL6984510 | 0.77 | — | — | |
| SCHEMBL9792336 | 0.76 | ALOX15 (0.46) | ALDH1A1 | |
| SCHEMBL15344657 | 0.75 | PTPN1 (0.31) | — | |
| SCHEMBL28500467 | 0.75 | CHRNB2 (0.44) | — | |
| SCHEMBL8064691 | 0.75 | — | — | |
| SCHEMBL10547596 | 0.75 | LMNA (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074108-B3 | RENIN INHIBITORS | VITAE PHARMACEUTICALS INC (US) | 2013-06-26 | — | — | EP | disclosed |