Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1763775 | 0.66 | PDE3B (0.37) | IDH1XDH | |
| SCHEMBL31465468 | 0.62 | XDH (0.41) | SMN1; SMN2XDH | |
| SCHEMBL17506443 | 0.60 | MAPK14 (0.33) | — | |
| SCHEMBL1830255 | 0.60 | GRM5 (0.34) | — | |
| SCHEMBL4591162 | 0.59 | KCNH2 (0.43) | — | |
| SCHEMBL12807167 | 0.59 | KCNH2 (0.40) | SMN1; SMN2 | |
| SCHEMBL2793062 | 0.58 | KCNH2 (0.47) | — | |
| SCHEMBL2431484 | 0.58 | TYRO3 (0.49) | XDH | |
| Ammonia Solution, Strong SCHEMBL29135408 | 0.57 | KCNH2 (0.45) | SMN1; SMN2 | |
| SCHEMBL30099906 | 0.56 | GPR84 (0.44) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2610256-A1 | Pyrimidine derivatives as protein kinase inhibitors | Cyclacel Limited (GB) | 2013-07-03 | — | — | EP | disclosed |