Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 6/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10006551 | 0.74 | DUT (0.44) | PDE2APDE3BPDE3AHPGDP2RY12 | |
| SCHEMBL30099906 | 0.72 | GPR84 (0.44) | XDHGPR84 | |
| SCHEMBL2431484 | 0.71 | TYRO3 (0.49) | XDHPDE3BPDE3AP2RY12GPR84 | |
| SCHEMBL10006861 | 0.70 | PDE3B (0.47) | PDE2APDE3BPDE3AMEN1KMT2A | |
| SCHEMBL12830376 | 0.70 | PDE3B (0.47) | PDE2APDE3BPDE3AMEN1KMT2A | |
| SCHEMBL18759700 | 0.69 | MAPT (0.35) | XDHHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4566029 | 0.69 | XDH (0.41) | XDHPKMHPGDGPR84 | |
| SCHEMBL3260370 | 0.67 | XDH (0.39) | XDHADORA3ADORA2AGPR84 | |
| SCHEMBL30642609 | 0.66 | GPR84 (0.37) | XDHGPR84 | |
| SCHEMBL10553318 | 0.65 | KMT2A (0.56) | MEN1KMT2AMAPTPKMGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049253-A1 | BRIDGED CYCLE‑BASED INHIBITORS OF DNA‑DEPENDENT PROTEIN KINASE AND COMPOSITIONS AND APPLICATION IN GENE EDITING | JUNO THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |