Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27999689 | 0.77 | — | — | |
| SCHEMBL18553375 | 0.75 | — | — | |
| SCHEMBL28193776 | 0.75 | — | — | |
| SCHEMBL3279311 | 0.75 | — | — | |
| SCHEMBL9523803 | 0.75 | ECE1 (0.46) | ECE1KDM4EPLA2G2AHTTLMNA | |
| SCHEMBL10002701 | 0.74 | — | — | |
| SCHEMBL429295 | 0.74 | — | — | |
| SCHEMBL12999522 | 0.74 | ECE1 (0.50) | ECE1KDM4EPLA2G2AHTTLMNA | |
| SCHEMBL2185099 | 0.74 | EGLN1 (0.41) | ECE1KDM4EPLA2G2ALMNAEGLN1 | |
| SCHEMBL501649 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121802-B1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | ALCON INC (CH) | 2024-07-17 | — | — | EP | claimed |
| EP-4121279-B1 | METHOD FOR PRODUCING EMBEDDED OR HYBRID HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2024-07-10 | — | — | EP | claimed |
| EP-4076916-B1 | WETTABLE SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2024-06-12 | — | — | EP | claimed |
| EP-4369081-A2 | METHOD FOR PRODUCING AN OPHTHALMIC PRODUCT | Alcon Inc. (CH) | 2024-05-15 | — | — | EP | claimed |
| EP-4121801-B1 | INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX | ALCON INC (CH) | 2024-04-17 | — | — | EP | claimed |
| EP-3481897-B9 | SILICONE HYDROGELS COMPRISING POLYAMIDES | JOHNSON & JOHNSON VISION CARE (US) | 2024-04-10 | — | — | EP | claimed |
| EP-4146461-B1 | METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2024-03-13 | — | — | EP | claimed |
| EP-4118134-B1 | PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | ALCON INC (CH) | 2024-02-28 | — | — | EP | claimed |
| US-11867874-B2 | Insert materials with high oxygen permeability and high refractive index | ALCON INC. (CH) | 2024-01-09 | — | — | US | claimed |
| EP-3481897-B1 | SILICONE HYDROGELS COMPRISING POLYAMIDES | JOHNSON & JOHNSON VISION CARE (US) | 2024-01-03 | — | — | EP | claimed |
| US-20150094395-A1 | SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY | JOHNSON & JOHNSON VISION CARE (US) | 2015-04-02 | — | — | US | claimed |
| US-8937111-B2 | Silicone hydrogels comprising desirable water content and oxygen permeability | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2015-01-20 | — | — | US | claimed |
| US-8937110-B2 | Silicone hydrogels having a structure formed via controlled reaction kinetics | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2015-01-20 | — | — | US | claimed |
| US-20150011672-A1 | SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS | JOHNSON & JOHNSON VISION CARE (US) | 2015-01-08 | — | — | US | claimed |
| US-20140031449-A1 | SILICONE HYDROGELS FORMED FROM ZERO DILUENT REACTIVE MIXTURES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-01-30 | — | — | US | claimed |
| US-20140031447-A1 | SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-01-30 | — | — | US | claimed |
| US-20140024791-A1 | SILICONE HYDROGELS COMPRISING N-VINYL AMIDES AND HYDROXYALKYL (METH)ACRYLATES OR (METH)ACRYLAMIDES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-01-23 | — | — | US | claimed |
| US-20130217620-A1 | IONIC SILICONE HYDROGELS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-08-22 | — | — | US | claimed |
| US-20130172440-A1 | SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-07-04 | — | — | US | claimed |
| US-20130168617-A1 | IONIC SILICONE HYDROGELS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-07-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217620-A1 | IONIC SILICONE HYDROGELS | HACD2, IGFBP2, IGFBP6 | ECE1 2563/4885KDM4E 2259/4885PLA2G2A 3743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.