Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265822 | 0.88 | TSHR (0.50) | TSHRALDH1A1HSD17B10MGAMGAA | |
| SCHEMBL3392036 | 0.83 | ALDH1A1 (0.38) | TSHRALDH1A1HSD17B10KDM4ELMNA | |
| Alcohol SCHEMBL28286197 | 0.81 | TSHR (0.43) | TSHRALDH1A1HSD17B10MGAMGAA | |
| SCHEMBL27986981 | 0.81 | TSHR (0.41) | TSHRALDH1A1HSD17B10MGAMGAA | |
| SCHEMBL148546 | 0.79 | TSHR (0.43) | TSHRALDH1A1HSD17B10MGAMGAA | |
| SCHEMBL1262529 | 0.79 | — | — | |
| SCHEMBL12158758 | 0.79 | MGAM (0.50) | TSHRALDH1A1HSD17B10MGAMGAA | |
| SCHEMBL14532417 | 0.79 | MGAM (0.50) | TSHRALDH1A1HSD17B10MGAMGAA | |
| SCHEMBL26765970 | 0.79 | — | — | |
| SCHEMBL286783 | 0.79 | TSHR (0.43) | TSHRALDH1A1HSD17B10MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543439-A2 | NRF2 PROTEIN DEGRADERS | Ganymede Oncology, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024006742-A2 | NRF2 PROTEIN DEGRADERS | DRACEN PHARMACEUTICALS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |
| US-8957233-B2 | Method for producing optically active 1,2-bis(dialkylphosphino)benzene derivative | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2015-02-17 | — | — | US | disclosed |
| US-20130172597-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 1,2-BIS(DIALKYLPHOSPHINO)BENZENE DERIVATIVE | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2013-07-04 | — | — | US | disclosed |
| CN-1235898-C | Cyclohexenedioxythiochromanoyl derivatives | BASF AG (DE) | 2006-01-11 | — | — | CN | disclosed |
| CN-1149200-C | 2-[(dihydro)pyrazole-3'-oxymethylene] aniline amide and its preparation and use | �����ɷ� | 2004-05-12 | — | — | CN | disclosed |
| CN-1149216-C | Tricyclic Benzoylcyclohexanedione Derivatives | �����ɷ� | 2004-05-12 | — | — | CN | disclosed |
| CN-1364161-A | N-substituted perhydrodiazines | BASF AG (DE) | 2002-08-14 | — | — | CN | disclosed |
| CN-1308065-A | 2-[(dihydro)pyrazole-3'-oxymethylene] aniline amide and its preparation and use | BASF AG (DE) | 2001-08-15 | — | — | CN | disclosed |
| CN-1068313-C | Amide of 2- [ (dihydro) pyrazole-3' -oxymethylene ] aniline, preparation method and application thereof | BASF AG (DE) | 2001-07-11 | — | — | CN | disclosed |
| CN-1066137-C | Alpha-phenylbutenic acid methyl esters | BASF AG (DE) | 2001-05-23 | — | — | CN | disclosed |
| CN-1166828-A | 2-(4-biphenyl-oxymethlene) anilides, process and intermediate products for preparing the same and their use as pesticides | BASF AG (DE) | 1997-12-03 | — | — | CN | disclosed |
| CN-1154692-A | Amide of 2- [ (dihydro) pyrazole-3' -oxymethylene ] aniline, preparation method and application thereof | BASF AG (DE) | 1997-07-16 | — | — | CN | disclosed |
| CN-1150800-A | Alpha-phenylbutenic acid methyl ester | BASF AG (DE) | 1997-05-28 | — | — | CN | disclosed |
| CN-1098713-A | The ortho-ethenylphenylacetic acid derivatives that replaces | BASF AG (DE) | 1995-02-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172597-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 1,2-BIS(DIALKYLPHOSPHINO)BENZENE DERIVATIVE | RDX, BRIX1, P2RX1 | TSHR 1809/4885ALDH1A1 2562/4885HSD17B10 3398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.