SCHEMBL150645

SCHEMBL150645

NCCCC[C@H](N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O

nearest known ligand 0.83

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ BDKRB2 P30411 13/20 0.83
▸ F2 P00734 1/20 0.69
▸ PREP P48147 1/20 0.61
▸ MRGPRX2 Q96LB1 1/20 0.60
▸ OPRD1 P41143 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1649860 1.00 BDKRB2 (0.83) BDKRB2F2PREPMRGPRX2OPRD1
SCHEMBL20298769 0.99 BDKRB2 (0.81) BDKRB2F2PREPMRGPRX2OPRD1
SCHEMBL29930311 0.95 BDKRB2 (0.76) BDKRB2F2OPRD1
Bradykinin SCHEMBL3047797 0.94 BDKRB2 (0.82) BDKRB2F2PREPMRGPRX2OPRD1
Bradykinin SCHEMBL29530927 0.92 BDKRB2 (0.79) BDKRB2F2PREPMRGPRX2OPRD1
SCHEMBL29484957 0.92 BDKRB2 (0.79) BDKRB2F2PREPMRGPRX2OPRD1
SCHEMBL29404860 0.92 BDKRB2 (0.79) BDKRB2F2PREPMRGPRX2OPRD1
SCHEMBL25335885 0.91 BDKRB2 (0.68) BDKRB2F2OPRD1
SCHEMBL30526215 0.91 BDKRB2 (0.68) BDKRB2F2OPRD1
SCHEMBL20298701 0.90 BDKRB2 (0.75) BDKRB2F2PREPOPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2714 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12558420-B2 Methods for treating inflammation using antibodies to kallidin and des-Arg10-kallidin SANOFI (FR) 2026-02-24 — — US claimed
EP-4680233-A2 ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE Cognition Therapeutics, Inc. (US) 2026-01-21 — — EP claimed
US-12297227-B2 Method for extracting target protein from biological sample and method for analyzing target protein MEDIFORD CORPORATION (JP) 2025-05-13 — — US claimed
WO-2024196799-A2 ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE COGNITION THERAPEUTICS, INC. (US) 2024-09-26 — — WO claimed
US-20230399388-A1 METHODS FOR TREATING INFLAMMATION USING ANTIBODIES TO KALLIDIN AND DES-ARG10-KALLIDIN SANOFI (FR) 2023-12-14 — — US claimed
WO-2023183932-A2 MONOBODIES BINDING TO INTERCELLULAR ADHESION MOLECULE 2 (ICAM-2) NEW YORK UNIVERSITY (US) 2023-09-28 — — WO claimed
US-20230184786-A1 Methods of Detecting and Treating Immune Responses Associated with Viral Infection FORSYTH DENTAL INFIRMARY FOR CHILDREN, d/b/a THE FORSYTH INSTITUTE 2023-06-15 — — US claimed
CN-114778746-B Method for detecting 9 alkaloids in blood by liquid chromatography-tandem mass spectrometry and application 北京和合医学诊断技术股份有限公司 2022-09-20 — — CN claimed
CN-114191628-A Double-chin beautifying, degreasing and shaping method 大连绚素医疗美容诊所有限公司 2022-03-18 — — CN claimed
CN-113773385-A Antibodies to bradykinin B1 receptor ligands 赛诺菲 2021-12-10 — — CN claimed
US-5039660-A Partially fused peptide pellet ENDOCON, INC. (US) 1991-08-13 — — US claimed
CN-1046098-A PARTIALLY FUSED PELLET AS SUBCUTANEOUS DRUG DELIVERY ENDOCON INC (US) 1990-10-17 — — CN claimed
WO-1990010437-A1 PARTIALLY FUSED PEPTIDE PELLET ENDOCON, INC. (US) 1990-09-20 — — WO claimed
EP-0272929-A2 Enkephalinase for therapeutic use GENENTECH, INC. (US) 1988-06-29 — — EP claimed
EP-0207402-A2 Process for producing proteins and polypeptides BAYER AG (DE) 1987-01-07 — — EP claimed
US-4283392-A Infusion solutions containing amino acids and mineral salts THERA GESELLSCHAFT FUR PATENTVERWERTUNG MBH (DE) 1981-08-11 — — US claimed
EP-0010587-A1 Adamantylalkyloxy-carbonyl derivatives, their preparation and their use for the production of peptides Kalbacher, Hubert (DE) 1980-05-14 — — EP claimed
US-4177261-A ALBUMIN-FREED CALF BLOOD EXTRACT AND BRADY KININ AND KALLIDIN THERA GESELLSCHAFT FUR PATENTVERWERTUNG MBH (DE) 1979-12-04 — — US claimed
US-4150121-A Kinin containing injection composition THERA GESELLSCHAFT FUR PATENTVERWERTUNG MBH (DE) 1979-04-17 — — US claimed
US-4146613-A ORAL ANTI-DIABETIC DRUG COMPOSITION THERA GESELLSCHAFT FUR PATENTVERWERTUNG MBH (DE) 1979-03-27 — — US claimed
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