SCHEMBL20298769

SCHEMBL20298769

NCCCC[C@H](N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.81

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ BDKRB2 P30411 12/20 0.81
▸ F2 P00734 1/20 0.67
▸ OPRD1 P41143 3/20 0.60
▸ PREP P48147 1/20 0.59
▸ MRGPRX2 Q96LB1 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1649860 0.99 BDKRB2 (0.83) BDKRB2F2OPRD1PREPMRGPRX2
SCHEMBL150645 0.99 BDKRB2 (0.83) BDKRB2F2OPRD1PREPMRGPRX2
SCHEMBL29930311 0.95 BDKRB2 (0.76) BDKRB2F2OPRD1
SCHEMBL29404860 0.93 BDKRB2 (0.79) BDKRB2F2OPRD1PREPMRGPRX2
SCHEMBL29484957 0.93 BDKRB2 (0.79) BDKRB2F2OPRD1PREPMRGPRX2
Bradykinin SCHEMBL3047797 0.93 BDKRB2 (0.82) BDKRB2F2OPRD1PREPMRGPRX2
Bradykinin SCHEMBL29530927 0.91 BDKRB2 (0.79) BDKRB2F2OPRD1PREPMRGPRX2
SCHEMBL20298701 0.91 BDKRB2 (0.75) BDKRB2F2OPRD1PREP
SCHEMBL31289571 0.91 BDKRB2 (0.66) BDKRB2F2OPRD1
SCHEMBL30672603 0.91 BDKRB2 (0.66) BDKRB2F2OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12558420-B2 Methods for treating inflammation using antibodies to kallidin and des-Arg10-kallidin SANOFI (FR) 2026-02-24 — — US claimed
US-20230399388-A1 METHODS FOR TREATING INFLAMMATION USING ANTIBODIES TO KALLIDIN AND DES-ARG10-KALLIDIN SANOFI (FR) 2023-12-14 — — US claimed
US-20230184786-A1 Methods of Detecting and Treating Immune Responses Associated with Viral Infection FORSYTH DENTAL INFIRMARY FOR CHILDREN, d/b/a THE FORSYTH INSTITUTE 2023-06-15 — — US claimed
EP-4192843-A1 PEPTIDES ABLE TO BIND ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND MEDICAL USES THEREOF Ospedale Pediatrico Bambino Gesù (IT) 2023-06-14 — — EP claimed
EP-4105658-A1 IMPROVED BIOASSAY METHOD Kashiv Biosciences, LLC (US) 2022-12-21 — — EP claimed
US-20220317111-A1 BIOASSAY METHOD AMNEAL PHARMACEUTICALS LLC 2022-10-06 — — US claimed
US-12558420-B2 Methods for treating inflammation using antibodies to kallidin and des-Arg10-kallidin SANOFI (FR) 2026-02-24 — — US disclosed
US-12558420-B2 Methods for treating inflammation using antibodies to kallidin and des-Arg10-kallidin SANOFI (FR) 2026-02-24 — — US disclosed
US-12558420-B2 Methods for treating inflammation using antibodies to kallidin and des-Arg10-kallidin SANOFI (FR) 2026-02-24 — — US disclosed
US-12427209-B2 Dual mode 18F-labelled theranostic compounds and uses thereof PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-09-30 — — US disclosed
CN-113773385-B Antibodies to bradykinin B1 receptor ligands 赛诺菲 2025-09-12 — — CN disclosed
CN-120441698-A Antibodies to bradykinin B1 receptor ligands 赛诺菲 2025-08-08 — — CN disclosed
US-20250241600-A1 MULTI-DISEASE PATIENT MANAGEMENT CARDIAC PACEMAKERS INC (US) 2025-07-31 — — US disclosed
EP-3558960-B1 CARBOXYLIC ACID AROMATIC AMIDES AS ANTAGONISTS OF BRADYKININ B1 RECEPTOR Bayer Pharma AG (DE) 2022-01-05 — — EP disclosed
US-20210317092-A1 TETRAZOLE CONTAINING COMPOUNDS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2021-10-14 — — US disclosed
EP-3558972-A1 TETRAZOLE CONTAINING COMPOUNDS Bayer Pharma Aktiengesellschaft (DE) 2019-10-30 — — EP disclosed
EP-3558960-A1 CARBOXYLIC ACID AROMATIC AMIDES AS ANTAGONISTS OF BRADYKININ B1 RECEPTOR Bayer Pharma Aktiengesellschaft (DE) 2019-10-30 — — EP disclosed
US-20190177279-A1 CARBOXYLIC ACID AROMATIC 1,2-CYCLOPROPYLAMIDES Bayer Pharma AG (DE) 2019-06-13 — — US disclosed
WO-2018114786-A1 CARBOXYLIC ACID AROMATIC AMIDES AS ANTAGONISTS OF BRADYKININ B1 RECEPTOR BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-06-28 — — WO disclosed
WO-2018114783-A1 TETRAZOLE CONTAINING COMPOUNDS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-06-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12427209-B2 Dual mode 18F-labelled theranostic compounds and uses thereof TFRC, SLC39A3, SLC39A14 BDKRB2 2974/4885F2 2281/4885OPRD1 4276/4885
US-20210317092-A1 TETRAZOLE CONTAINING COMPOUNDS TSLP, IL5, TRPA1 BDKRB2 297/4885F2 329/4885OPRD1 882/4885
US-12558420-B2 Methods for treating inflammation using antibodies to kallidin and des-Arg10-kallidin BDKRB2, KLKB1, BDKRB1 BDKRB2 1/4885F2 155/4885OPRD1 819/4885
US-20190177279-A1 CARBOXYLIC ACID AROMATIC 1,2-CYCLOPROPYLAMIDES PAH, DDC, RIMKLA BDKRB2 1156/4885F2 2114/4885OPRD1 701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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