SCHEMBL15065197

SCHEMBL15065197

CC[B-](CC)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
ALDH1A1 P00352 2/20 0.37
PSIP1 O75475 1/20 0.35
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
MAPT P10636 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
KCNN4 O15554 1/20 0.32
CALM1 P0DP23 1/20 0.32
HPGD P15428 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
LTA4H P09960 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1040893 0.77 TP53 (0.41) TP53ALDH1A1PSIP1LMNASMN1; SMN2
SCHEMBL8757598 0.77 TP53 (0.41) TP53ALDH1A1PSIP1LMNASMN1; SMN2
SCHEMBL309096 0.76 TP53 (0.42) TP53SMN1; SMN2TSHRLTA4H
Lithium Ion SCHEMBL7107316 0.74 TP53 (0.39) TP53ALDH1A1PSIP1LMNASMN1; SMN2
SCHEMBL21810707 0.74 TP53 (0.39) TP53ALDH1A1PSIP1LMNASMN1; SMN2
Lithium Ion SCHEMBL4652452 0.74 TP53 (0.39) TP53ALDH1A1PSIP1LMNASMN1; SMN2
SCHEMBL9767891 0.74 TP53 (0.40) TP53SMN1; SMN2TSHRLTA4H
Silver SCHEMBL9156386 0.74 TP53 (0.40) TP53SMN1; SMN2TSHRLTA4H
SCHEMBL4530067 0.74 SIGMAR1 (0.44) TP53SMN1; SMN2TSHRCES2CES1
SCHEMBL3321392 0.74 TP53 (0.40) TP53SMN1; SMN2TSHRLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364382-B2 Curable polysiloxane compositions and pressure sensitive adhesives made therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-07-30 US disclosed
EP-2797985-B1 CURABLE-ON-DEMAND POLYSILOXANE COATING COMPOSITION 3M INNOVATIVE PROPERTIES CO (US) 2015-09-23 EP disclosed
US-9035008-B2 Curable-on-demand polysiloxane coating composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-05-19 US disclosed
US-20140377494-A1 Curable Polysiloxane Compositions and Pressure Sensitive Adhesives Made Therefrom 3M INNOVATIVE PROPERTIES COMPANY 2014-12-25 US disclosed
US-20140349125-A1 CURABLE-ON-DEMAND POLYSILOXANE COATING COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY 2014-11-27 US disclosed
EP-2797985-A1 CURABLE-ON-DEMAND POLYSILOXANE COATING COMPOSITION 3M Innovative Properties Company (US) 2014-11-05 EP disclosed
EP-2798011-A1 CURABLE POLYSILOXANE COMPOSITIONS AND PRESSURE SENSITIVE ADHESIVES MADE THEREFROM 3M Innovative Properties Company (US) 2014-11-05 EP disclosed
WO-2013101535-A1 CURABLE POLYSILOXANE COMPOSITIONS AND PRESSURE SENSITIVE ADHESIVES MADE THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-07-04 WO disclosed
WO-2013101742-A1 CURABLE-ON-DEMAND POLYSILOXANE COATING COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-07-04 WO disclosed