SCHEMBL574585

SCHEMBL574585

Clc1ccc2c(C#Cc3ccccc3)c3ccccc3c(C#Cc3ccccc3)c2c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.44
PTGDR2 Q9Y5Y4 1/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
AHR P35869 1/20 0.39
ASIC3 Q9UHC3 2/20 0.39
GRM4 Q14833 1/20 0.39
GRM5 P41594 2/20 0.38
MAPT P10636 1/20 0.36
AKR1C2 P52895 1/20 0.36
AKR1C1 Q04828 1/20 0.36
KCNH2 Q12809 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ADORA2A P29274 1/20 0.35
ADK P55263 1/20 0.35
FLT3 P36888 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29379887 1.00 APP (0.44) APPPTGDR2ATMTDP1L3MBTL1
SCHEMBL15065239 0.88 GRM4 (0.36) APPPTGDR2ATMTDP1L3MBTL1
SCHEMBL28698877 0.85 MAPT (0.39) APPPTGDR2ATMTDP1L3MBTL1
SCHEMBL30459389 0.85 APP (0.48) APPATMTDP1L3MBTL1AHR
SCHEMBL429961 0.85 APP (0.48) APPATMTDP1L3MBTL1AHR
SCHEMBL391401 0.82 KCNH2 (0.47) APPATMTDP1L3MBTL1ASIC3
SCHEMBL29357652 0.82 APP (0.67) APPATMTDP1L3MBTL1GRM5
SCHEMBL55761 0.82 APP (0.67) APPATMTDP1L3MBTL1GRM5
SCHEMBL29787236 0.80 APP (0.52) APPATMTDP1L3MBTL1ASIC3
SCHEMBL442909 0.79 APP (0.50) APPATMTDP1L3MBTL1ASIC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 396 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250084452-A1 BIOLOGICAL INDICATOR FOR DETERMINING THE EFFICACY OF A STERILIZATION PROCESS AND METHODS OF USE TERRAGENE LLC 2025-03-13 US claimed
US-20230357630-A1 HEAVY-ATOM FREE SENSITIZERS FOR TRIPLET-TRIPLET ANNIHILATION UPCONVERSION SYSTEMS UNIVERSITY OF WASHINGTON (US) 2023-11-09 US claimed
US-11629203-B2 Photopolymerisable composition, material obtained by polymerising such a composition and 3D printing method using such a composition ECOLE NORMALE SUPERIEURE DE LYON (FR) 2023-04-18 US claimed
US-11371085-B2 Reagents and methods for isothermal chain reaction MANCEBO RICARDO (US) 2022-06-28 US claimed
US-20210189156-A1 PHOTOPOLYMERISABLE COMPOSITION, MATERIAL OBTAINED BY POLYMERISING SUCH A COMPOSITION AND 3D PRINTING METHOD USING SUCH A COMPOSITION ECOLE NORMALE SUPERIEURE DE LYON (FR) 2021-06-24 US claimed
US-20210041362-A1 METHOD FOR CALIBRATING FLUORESCENT PLATE READERS PLEXBIO CO LTD (TW) 2021-02-11 US claimed
EP-3661974-A1 PHOTOPOLYMERISABLE COMPOSITION, MATERIAL OBTAINED BY POLYMERISING SUCH A COMPOSITION AND 3D PRINTING METHOD USING SUCH A COMPOSITION Ecole Normale Superieure De Lyon (FR) 2020-06-10 EP claimed
US-10612077-B2 Reagents and methods for isothermal chain reaction Mancebo, Ricardo (US) 2020-04-07 US claimed
WO-2019025717-A1 PHOTOPOLYMERISABLE COMPOSITION, MATERIAL OBTAINED BY POLYMERISING SUCH A COMPOSITION AND 3D PRINTING METHOD USING SUCH A COMPOSITION ECOLE NORMALE SUPERIEURE DE LYON (FR) 2019-02-07 WO claimed
US-20170284942-A1 METHOD FOR CALIBRATING FLUORESCENT PLATE READERS PLEXBIO CO., LTD (TW) 2017-10-05 US claimed
US-7956989-B2 Surface plasmon assisted microscope UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) 2011-06-07 US claimed
US-20110089317-A1 Polarization Standards for Microscopy UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORTH WORTH (US) 2011-04-21 US claimed
US-7901852-B2 Metrology of bilayer photoresist processes FREESCALE SEMICONDUCTOR, INC. (US) 2011-03-08 US claimed
US-20100055713-A1 CHEMILUMINESCENCE SENSOR ARRAY SUNDARARAJAN NARAYAN 2010-03-04 US claimed
US-20090218516-A1 Ratiometric Surface Plasmon Coupled Emission Detector UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) 2009-09-03 US claimed
US-20090220895-A1 Metrology of bilayer photoresist processes FREESCALE SEMICONDUCTOR, INC. 2009-09-03 US claimed
US-7537934-B2 For monitoring molecular binding; integrated assay device comprising chemiluminescent material, biopolymer and a light detector; identify antigen binding to antibodies INTEL CORPORATION (US) 2009-05-26 US claimed
US-20080231834-A1 SURFACE PLASMON ASSISTED MICROSCOPE UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) 2008-09-25 US claimed
US-20070154967-A1 For monitoring molecular binding; integrated assay device comprising chemiluminescent material, biopolymer and a light detector; identify antigen binding to antibodies INTEL CORPORATION (US) 2007-07-05 US claimed
US-4076645-A FROM REACTION OF BIS(6-CARBOPENTOXY-2,4,5-TRICHLOROPHENYL)OXALATE WITH A PEROXIDE; 9,10-BIS(PHENYLETHYNYL)ANTHRACENE, DILUENT AMERICAN CYANAMID COMPANY (US) 1978-02-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357630-A1 HEAVY-ATOM FREE SENSITIZERS FOR TRIPLET-TRIPLET ANNIHILATION UPCONVERSION SYSTEMS SLC6A4, TST, SLC6A6 APP 899/4885PTGDR2 4472/4885ATM 28/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.