Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15065902 | 0.81 | SLC6A2 (0.51) | CASP1GAATSHRSLC6A2SLC6A3 | |
| SCHEMBL15065610 | 0.80 | SLC6A4 (0.49) | SLC6A2SLC6A3SLC6A4KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9427139 | 0.79 | CASP1 (0.58) | CASP1GAATSHRLMNAMEN1 | |
| SCHEMBL15066405 | 0.79 | SLC6A2 (0.54) | CASP1GAATSHRSLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL9427976 | 0.79 | CASP1 (0.61) | CASP1GAATSHRSLC6A2SLC6A3 | |
| SCHEMBL872307 | 0.78 | SLC6A3 (0.61) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL15066357 | 0.78 | SLC6A2 (0.53) | CASP1GAATSHRSLC6A2SLC6A3 | |
| SCHEMBL15066388 | 0.78 | SLC6A2 (0.50) | CASP1GAATSHRSLC6A2SLC6A3 | |
| SCHEMBL557875 | 0.77 | CASP1 (0.62) | CASP1GAATSHRSLC6A2SLC6A3 | |
| SCHEMBL15066503 | 0.77 | SLC6A2 (0.53) | CASP1GAATSHRSLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104039753-B | The compositions of phenylcycloalkyl methylamine derivative, synthesis and using method | 雷维瓦药品公司 | 2016-09-14 | — | — | CN | disclosed |
| EP-2797870-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PHENYLCYCLOALKYLMETHYLAMINE DERIVATIVES | Reviva Pharmaceuticals, Inc. (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013102195-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PHENYLCYCLOALKYLMETHYLAMINE DERIVATIVES | REVIVA PHARMACEUTICALS, INC. (US) | 2013-07-04 | — | — | WO | disclosed |