Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL799541 | 0.78 | TSHR (0.61) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL21691223 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL82230 | 0.77 | NOTUM (0.47) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| SCHEMBL19785388 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL9912479 | 0.76 | TSHR (0.46) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL19544821 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL12203436 | 0.74 | TSHR (0.44) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL10610735 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL23589380 | 0.73 | GABRA1 (0.40) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL179527 | 0.73 | ALDH1A1 (0.64) | ALDH1A1HPGDALOX15HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11306084-B2 | Integrin antagonists | SAINT LOUIS UNIVERSITY (US) | 2022-04-19 | — | — | US | disclosed |
| WO-2021129724-A1 | ARYLAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | 陕西莱特光电材料股份有限公司 | 2021-07-01 | — | — | WO | disclosed |
| US-20190345155-A1 | INTEGRIN ANTAGONISTS | Indalo Therapeutics, Inc. | 2019-11-14 | — | — | US | disclosed |
| US-20190345155-A1 | INTEGRIN ANTAGONISTS | Indalo Therapeutics, Inc. | 2019-11-14 | — | — | US | disclosed |
| EP-3562826-A1 | INTEGRIN ANTAGONISTS | Saint Louis University (US) | 2019-11-06 | — | — | EP | disclosed |
| WO-2018132268-A1 | INTEGRIN ANTAGONISTS | SAINT LOUIS UNIVERSITY (US) | 2018-07-19 | — | — | WO | disclosed |
| EP-1971595-B1 | CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2013-10-16 | — | — | EP | disclosed |
| US-7910592-B2 | CETP inhibitors | MERCK SHARP & DOHME CORP. (US) | 2011-03-22 | — | — | US | disclosed |
| US-7906503-B2 | Substituted 3-alkyl and 3-alkenyl azetidine derivatives | MERCK SHARP & DOHME CORP. (US) | 2011-03-15 | — | — | US | disclosed |
| US-20090069284-A1 | Substituted 3-alkyl and 3-alkenyl azetidine derivatives | MERCK SHARP & DOHME CORP. | 2009-03-12 | — | — | US | disclosed |
| US-20090042892-A1 | Cetp Inhibitors | MERCK SHARP & DOHME LLC | 2009-02-12 | — | — | US | disclosed |
| US-7485732-B2 | Substituted 3-alkyl and 3-alkenyl azetidine derivatives | MERCK & CO., INC. (US) | 2009-02-03 | — | — | US | disclosed |
| US-7485732-B2 | Substituted 3-alkyl and 3-alkenyl azetidine derivatives | MERCK & CO., INC. (US) | 2009-02-03 | — | — | US | disclosed |
| EP-1971595-A2 | CETP INHIBITORS | Merck & Co., Inc. (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081569-A2 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042892-A1 | Cetp Inhibitors | CETP, APOB, MTTP | ALDH1A1 3603/4885HPGD 2538/4885ALOX15 1762/4885 |
| US-20190345155-A1 | INTEGRIN ANTAGONISTS | ITGA5, ITGB5, ITGB2 | ALDH1A1 749/4885HPGD 2427/4885ALOX15 3010/4885 |
| US-20090069284-A1 | Substituted 3-alkyl and 3-alkenyl azetidine derivatives | CNR1, CNR2, MAG | ALDH1A1 2399/4885HPGD 3845/4885ALOX15 492/4885 |
| US-11306084-B2 | Integrin antagonists | ITGA5, ITGB5, ITGB2 | ALDH1A1 749/4885HPGD 2427/4885ALOX15 3010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.