SCHEMBL1506584

SCHEMBL1506584

C=COCCOCCOC=C.C=COCCOc1ccc(C(C)(C)c2ccc(OCCOC=C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.46
PSMB1 P20618 1/20 0.44
PSMB5 P28074 1/20 0.44
PSMB2 P49721 1/20 0.44
KDM4E B2RXH2 10/20 0.44
ALDH1A1 P00352 9/20 0.44
GAA P10253 1/20 0.43
MEN1 O00255 6/20 0.41
KMT2A Q03164 6/20 0.41
TP53 P04637 3/20 0.41
MAPT P10636 3/20 0.41
TSHR P16473 3/20 0.41
HPGD P15428 2/20 0.41
HIF1A Q16665 2/20 0.41
CYP1A2 P05177 1/20 0.41
PPARG P37231 1/20 0.41
POLB P06746 2/20 0.40
LMNA P02545 3/20 0.40
HTT P42858 2/20 0.40
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2471818 0.95 SMN1; SMN2 (0.50) SMN1; SMN2PSMB1PSMB5PSMB2KDM4E
SCHEMBL12136354 0.86 SMN1; SMN2 (0.47) SMN1; SMN2PSMB1PSMB5PSMB2KDM4E
SCHEMBL11789508 0.85 KDM4E (0.49) SMN1; SMN2KDM4EALDH1A1GAAMEN1
SCHEMBL905336 0.85 KDM4E (0.41) SMN1; SMN2PSMB1PSMB5PSMB2KDM4E
SCHEMBL1506586 0.83 SMN1; SMN2 (0.40) SMN1; SMN2PSMB1PSMB5PSMB2KDM4E
SCHEMBL16900536 0.83 SMN1; SMN2 (0.40) SMN1; SMN2PSMB1PSMB5PSMB2KDM4E
SCHEMBL8755135 0.82 ALDH1A1 (0.48) SMN1; SMN2PSMB1PSMB5PSMB2KDM4E
SCHEMBL13925376 0.81 DRD2 (0.44) KDM4EALDH1A1HPGDLMNAHTT
SCHEMBL9192499 0.81 APP (0.51) SMN1; SMN2KDM4EALDH1A1MEN1KMT2A
SCHEMBL419937 0.80 THRB (0.41) KDM4EALDH1A1MAPTHTTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8067145-B2 Developing solution and method for producing lithography printing plate FUJIFILM CORPORATION (JP) 2011-11-29 US disclosed
US-20110134411-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR, LITHOGRAPHIC PRINTING METHOD AND PACKAGED BODY OF LITHOGRAPHIC PRINTING PLATE PRECURSORS MITSUMOTO TOMOYOSHI 2011-06-09 US disclosed
US-7910286-B2 Lithographic printing plate precursor, lithographic printing method and packaged body of lithographic printing plate precursors FUJIFILM CORPORATION (JP) 2011-03-22 US disclosed
US-20070178414-A1 Developing solution and method for producing lithography printing plate FUJIFILM CORPORATION (JP) 2007-08-02 US disclosed