Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593380 | 0.85 | CNR1 (0.48) | ALDH1A1LMNAALOX15HSD17B10TDP1 | |
| SCHEMBL729772 | 0.83 | AOC3 (0.51) | CA1CA2ALDH1A1LMNAALOX15 | |
| SCHEMBL3436081 | 0.82 | NPC1 (0.60) | CA1CA2ALDH1A1LMNAALOX15 | |
| SCHEMBL7749333 | 0.81 | NQO1 (0.56) | ALDH1A1TDP1CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL7166618 | 0.80 | CYP3A4 (0.59) | CA1CA2ALDH1A1LMNAALOX15 | |
| SCHEMBL6865347 | 0.80 | LMNA (0.49) | CA1CA2ALDH1A1LMNAALOX15 | |
| SCHEMBL989033 | 0.80 | TAAR1 (0.56) | CA1CA2ALDH1A1LMNAALOX15 | |
| SCHEMBL18622727 | 0.80 | CA1 (0.48) | CA1CA2ALDH1A1LMNAALOX15 | |
| SCHEMBL10876942 | 0.79 | NR1H4 (0.47) | ALDH1A1LMNAMAPK1CYP3A4SMN1; SMN2 | |
| SCHEMBL9559033 | 0.79 | EPHX2 (0.47) | LMNACYP3A4SMN1; SMN2MAPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115006406-A | Stable olanzapine preparation | 南京清普生物科技有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-112006981-A | Long-acting compound insect repellent liquid preparation and preparation method and application thereof | 瑞普（天津）生物药业有限公司 | 2020-12-01 | — | — | CN | claimed |
| CN-107333766-B | Slow-release snake repellent | 中国人民解放军62040部队 | 2020-01-10 | — | — | CN | claimed |
| CN-112006981-B | Long-acting compound anthelmintic liquid preparation and preparation method and application thereof | 瑞普（天津）生物药业有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-115006406-A | Stable olanzapine preparation | 南京清普生物科技有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-114306233-A | Agomelatine self-microemulsion preparation | 常州恒邦药业有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-112006981-A | Long-acting compound insect repellent liquid preparation and preparation method and application thereof | 瑞普（天津）生物药业有限公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-107333766-B | Slow-release snake repellent | 中国人民解放军62040部队 | 2020-01-10 | — | — | CN | disclosed |
| CN-106344509-B | Cefquinome sulfate oil suspension and preparation method thereof | 成都乾坤动物药业股份有限公司 | 2020-01-03 | — | — | CN | disclosed |
| CN-106265506-B | Amoxicillin colistin sulfate oil suspension and preparation method thereof | 成都乾坤动物药业股份有限公司 | 2019-12-06 | — | — | CN | disclosed |
| US-8865707-B2 | Cholesteryl ester transfer protein inhibitors | MERCK SHARP & DOHME CORP. (US) | 2014-10-21 | — | — | US | disclosed |
| US-20090018054-A1 | Cholesteryl Ester Transfer Protein Inhibitors | MERCK SHARP & DOHME LLC | 2009-01-15 | — | — | US | disclosed |
| EP-1973546-A2 | CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | Merck & Co., Inc. (US) | 2008-10-01 | — | — | EP | disclosed |
| EP-1971595-A2 | CETP INHIBITORS | Merck & Co., Inc. (US) | 2008-09-24 | — | — | EP | disclosed |
| CN-100361653-C | Tiopronin soft capsule | HUAYUAN MEDICINE SCIENCE AND T (CN) | 2008-01-16 | — | — | CN | disclosed |
| WO-2007081570-A2 | CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | MERCK & CO., INC. (US) | 2007-07-19 | — | — | WO | disclosed |
| WO-2007081569-A2 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2007-07-19 | — | — | WO | disclosed |
| EP-0094085-B1 | ETHER COMPOUNDS, THEIR PRODUCTION AND AN INSECTICIDAL AND/OR ACARICIDAL COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-01-02 | — | — | EP | disclosed |
| US-4562213-A | Certain phenoxy-benzyloxy ether derivatives and an insecticidal and/or acaricidal composition containing the same and methods of use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-12-31 | — | — | US | disclosed |
| EP-0094085-A1 | Ether compounds, their production and an insecticidal and/or acaricidal composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018054-A1 | Cholesteryl Ester Transfer Protein Inhibitors | CETP, APOB, MTTP | CA1 4333/4885CA2 4477/4885ALDH1A1 1674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.